PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29117550-4 2017 We show that the nAChR gene acr-19 and alg-1, a key Argonaute-family member in the microRNA machinery, are specifically required for nicotine withdrawal response following chronic nicotine treatment. Nicotine 133-141 AcetylCholine Receptor Caenorhabditis elegans 28-34 29117550-4 2017 We show that the nAChR gene acr-19 and alg-1, a key Argonaute-family member in the microRNA machinery, are specifically required for nicotine withdrawal response following chronic nicotine treatment. Nicotine 180-188 AcetylCholine Receptor Caenorhabditis elegans 28-34 29117550-5 2017 Chronic exposure to nicotine downregulates alg-1, leading to upregulation of acr-19. Nicotine 20-28 AcetylCholine Receptor Caenorhabditis elegans 77-83