PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11533049-8 2001 As the G-463A polymorphism of the MPO gene, which strongly reduces myeloperoxidase mRNA expression, is associated with a reduced risk of lung cancer, chlorination damage of DNA /RNA and nucleosides by myeloperoxidase and its enhancement by nicotine may be important in the pathophysiology of human diseases associated with tobacco habits. Nicotine 240-248 myeloperoxidase Homo sapiens 34-37 11533049-8 2001 As the G-463A polymorphism of the MPO gene, which strongly reduces myeloperoxidase mRNA expression, is associated with a reduced risk of lung cancer, chlorination damage of DNA /RNA and nucleosides by myeloperoxidase and its enhancement by nicotine may be important in the pathophysiology of human diseases associated with tobacco habits. Nicotine 240-248 myeloperoxidase Homo sapiens 67-82 25806984-0 2015 Nicotine-enhanced oxidation of low-density lipoprotein and its components by myeloperoxidase/H2O2/Cl- system. Nicotine 0-8 myeloperoxidase Homo sapiens 77-92 25806984-1 2015 In this study, the effect of nicotine on the LDL oxidation by the MPO/H2O2/Cl- system and the effect of HOCl on LDL and some of its components, such as methyl linoleate, vitamin E and the amino acid tryptophan were explored. Nicotine 29-37 myeloperoxidase Homo sapiens 66-69 21724624-5 2012 Nicotine-dependent activation of leucocytes caused attenuation of endothelial nitric oxide (NO) bioavailability in the control group (P < 0.01), but not in MPO(low) individuals (P = 0.12); here the MPO burden of leucocytes correlated with the degree of vasomotor dysfunction (P = 0.008). Nicotine 0-8 myeloperoxidase Homo sapiens 201-204 19017736-6 2008 Being stimulated by nicotine, neutrophils generate reactive oxygen species and release prooxidant enzymes like myeloperoxidase, which are capable of entering the vessel wall independently. Nicotine 20-28 myeloperoxidase Homo sapiens 111-126