PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32638534-9	2020	Nicotine decreased the IL-1beta-induced IL-6 and MMP expression, in a dose-dependent manner, in WT chondrocytes but not in Chrna7-/- chondrocytes.	Nicotine	0-8	matrix metallopeptidase 3	Homo sapiens	49-52	
26553320-10	2016	Compared with the monoculture, MMP-1, MMP-3, interleukin (IL)-1beta, IL-6, IL-17, and IL-21 in supernatant of cocultures were markedly elevated after treatment with nicotine.	Nicotine	165-173	matrix metallopeptidase 3	Homo sapiens	38-43	
8976346-12	1996	Stromelysin-1 was up-regulated by nicotine and cotinine at 12 and 18 hours (1.5-fold to 7.0-fold).	Nicotine	34-42	matrix metallopeptidase 3	Homo sapiens	0-13