PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25762751-9	2015	During nicotine exposure, intact females displayed a decrease in CRF-R1, CRF-R2, Drd3, and Esr2 gene expression and an increase in CRF-BP.	Nicotine	7-15	dopamine receptor D3	Rattus norvegicus	81-85	
19995481-0	2010	The selective dopamine D3 receptor antagonist SB 277011-A, but not the partial agonist BP 897, blocks cue-induced reinstatement of nicotine-seeking.	Nicotine	131-139	dopamine receptor D3	Rattus norvegicus	14-34	
19995481-5	2010	SB 277011-A (1-10 mg/kg) was able to block cue-induced reinstatement of nicotine-seeking, indicating that DRD3 selective antagonism may be an effective approach to prevent relapse for nicotine.	Nicotine	72-80	dopamine receptor D3	Rattus norvegicus	106-110	
19995481-5	2010	SB 277011-A (1-10 mg/kg) was able to block cue-induced reinstatement of nicotine-seeking, indicating that DRD3 selective antagonism may be an effective approach to prevent relapse for nicotine.	Nicotine	184-192	dopamine receptor D3	Rattus norvegicus	106-110	
12610655-0	2003	Disruption of nicotine conditioning by dopamine D(3) receptor ligands.	Nicotine	14-22	dopamine receptor D3	Rattus norvegicus	39-61	
25907750-8	2015	These data reveal important age-dependent regulation of DRD1- and DRD3-related mRNAs during the course of nicotine exposure.	Nicotine	106-114	dopamine receptor D3	Rattus norvegicus	66-70	
25907750-9	2015	Furthermore, they highlight a requirement for DRD3 signaling in the development of adolescent nicotine sensitization, suggesting it may represent an appropriate target in the prevention of nicotine dependence initiated at this age.	Nicotine	94-102	dopamine receptor D3	Rattus norvegicus	46-50	
25907750-9	2015	Furthermore, they highlight a requirement for DRD3 signaling in the development of adolescent nicotine sensitization, suggesting it may represent an appropriate target in the prevention of nicotine dependence initiated at this age.	Nicotine	189-197	dopamine receptor D3	Rattus norvegicus	46-50	
20142301-1	2011	Our previous studies have shown that the selective dopamine D(3) receptor antagonists SB-277011A or NGB 2904 significantly attenuate cocaine self-administration under a progressive-ratio reinforcement schedule and cocaine-, methamphetamine- or nicotine-enhanced brain stimulation reward.	Nicotine	244-252	dopamine receptor D3	Rattus norvegicus	51-73	
16942635-0	2006	The selective dopamine D3 receptor antagonist SB-277011A reduces nicotine-enhanced brain reward and nicotine-paired environmental cue functions.	Nicotine	65-73	dopamine receptor D3	Rattus norvegicus	14-34	
16942635-0	2006	The selective dopamine D3 receptor antagonist SB-277011A reduces nicotine-enhanced brain reward and nicotine-paired environmental cue functions.	Nicotine	100-108	dopamine receptor D3	Rattus norvegicus	14-34	
12494400-0	2003	Increased dopamine D3 receptor expression accompanying behavioral sensitization to nicotine in rats.	Nicotine	83-91	dopamine receptor D3	Rattus norvegicus	10-30	
25907750-0	2015	Role of the D3 dopamine receptor in nicotine sensitization.	Nicotine	36-44	dopamine receptor D3	Rattus norvegicus	12-32	
25907750-5	2015	Nicotine-induced changes were seen for DRD3 and D3nf mRNAs in the nucleus accumbens shell early in repeated exposure in both age groups.	Nicotine	0-8	dopamine receptor D3	Rattus norvegicus	39-43