PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25381636-6 2015 In conclusion, nicotine-induced VCAM-1, MMP-2, and MMP-9 expressions occur in a dose-dependent fashion in both of the cell lines tested. Nicotine 15-23 vascular cell adhesion molecule 1 Mus musculus 32-38 25381636-0 2015 Nicotine-induced upregulation of VCAM-1, MMP-2, and MMP-9 through the alpha7-nAChR-JNK pathway in RAW264.7 and MOVAS cells. Nicotine 0-8 vascular cell adhesion molecule 1 Mus musculus 33-39 25381636-2 2015 In the present experiment, both the RAW264.7 and MOVAS cell lines were employed to examine the nicotine-induced modulation of VCAM-1, MMP-2, and MMP-9 expressions in macrophages and vascular smooth muscle cells. Nicotine 95-103 vascular cell adhesion molecule 1 Mus musculus 126-132 25381636-3 2015 Our results showed that nicotine concentrations of both 0.5 and 5 ng/ml induced VCAM-1, MMP-2, and MMP-9 upregulation, while a concentration of 50 ng/ml had a slight inhibitory effect and a concentration of 500 ng/ml showed a significant inhibitory effect. Nicotine 24-32 vascular cell adhesion molecule 1 Mus musculus 80-86 25381636-4 2015 When cells were pretreated with either SP600125 (JNK inhibitor) or PNU-282987 (alpha7-nAChR agonist) prior to nicotine exposure, the nicotine-induced upregulation of VCAM-1, MMP-2, MMP-9, and p-JNK was suppressed, with a joint treatment producing a more significant inhibitory effect. Nicotine 133-141 vascular cell adhesion molecule 1 Mus musculus 166-172 25381636-7 2015 Furthermore, the nicotine exposure equivalent to plasma levels found in regular smokers can augment VCAM-1, MMP-2, and MMP-9 expressions through the alpha7-nAChR-JNK pathway. Nicotine 17-25 vascular cell adhesion molecule 1 Mus musculus 100-106 18472096-11 2008 Furthermore, the expression of VEGF and bFGF within CNV and VCAM-1 in choroid beneath CNV was up-regulated in nicotine-exposed mice. Nicotine 110-118 vascular cell adhesion molecule 1 Mus musculus 60-66 18472096-13 2008 These effects may be partly due to indirect actions of nicotine on BMCs via other factors (e.g. VEGF or VCAM-1). Nicotine 55-63 vascular cell adhesion molecule 1 Mus musculus 104-110 25803997-0 2014 Nicotine-induced ICAM-1 and VCAM-1 expression in mouse cardiac vascular endothelial cell via p38 MAPK signaling pathway. Nicotine 0-8 vascular cell adhesion molecule 1 Mus musculus 28-34 25803997-2 2014 STUDY DESIGN: We determined the effect of nicotine on the expression of adhesion molecules, intercellular adhesion molecule (ICAM-1), and vascular cell adhesion molecule (VCAM-1) in mouse cardiac vascular endothelial cells and the involvement of important known intermediaries, namely p38 mitogen-activated protein kinase (MAPK) signaling pathway. Nicotine 42-50 vascular cell adhesion molecule 1 Mus musculus 171-177 25803997-3 2014 RESULTS: Our results indicate that nicotine can enhance the expression of ICAM-1 and VCAM-1 on mouse cardiac vascular endothelial cell via p38 MAPK signaling pathway, resulting in increased expression of the cellular adhesion molecules ICAM-1 and VCAM-1. Nicotine 35-43 vascular cell adhesion molecule 1 Mus musculus 85-91 25803997-3 2014 RESULTS: Our results indicate that nicotine can enhance the expression of ICAM-1 and VCAM-1 on mouse cardiac vascular endothelial cell via p38 MAPK signaling pathway, resulting in increased expression of the cellular adhesion molecules ICAM-1 and VCAM-1. Nicotine 35-43 vascular cell adhesion molecule 1 Mus musculus 247-253 25803997-4 2014 CONCLUSION: We demonstrate that 10(-6) M nicotine maximally enhances mouse cardiac vascular endothelial cell expression of ICAM-1 and VCAM-1 at 8 hours. Nicotine 41-49 vascular cell adhesion molecule 1 Mus musculus 134-140 21239632-4 2011 An analysis of the phenotype of isolated brain microvessels after nicotine exposure indicated higher expression of inflammatory mediators, cytokines (IL-1beta, TNF-alpha, and IL-18), chemokines (CCL2 and CX(3)CL1), and adhesion molecules (ICAM-1, VCAM-1, and P-selectins), and this was accompanied by enhanced leukocyte infiltration into brain during ischemia/reperfusion (P < 0.01). Nicotine 66-74 vascular cell adhesion molecule 1 Mus musculus 247-253