PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30856513-8	2019	In addition, Western blotting and quantitative real-time PCR showed that VSMCs exposed to nicotine underwent changes in the expression of differentiation markers (alpha-SMA, SM22alpha and osteopontin), confirming the role of nicotine in VSMC differentiation.	Nicotine	90-98	actin alpha 2, smooth muscle, aorta	Mus musculus	163-172	
28644870-9	2017	Furthermore, the mRNA expression of the pro-fibrogenic factors alpha-smooth muscle actin (alphaSMA), transforming growth factor-beta (TGF-beta), and collagen alpha1 (Col1) was enhanced in the high-concentration nicotine-treated group compared with the vehicle group after corneal injury.	Nicotine	211-219	actin alpha 2, smooth muscle, aorta	Mus musculus	63-88	
28644870-9	2017	Furthermore, the mRNA expression of the pro-fibrogenic factors alpha-smooth muscle actin (alphaSMA), transforming growth factor-beta (TGF-beta), and collagen alpha1 (Col1) was enhanced in the high-concentration nicotine-treated group compared with the vehicle group after corneal injury.	Nicotine	211-219	actin alpha 2, smooth muscle, aorta	Mus musculus	90-98	
28644870-10	2017	Immunohistochemical analysis also showed that the alphaSMA-positive area was increased in chronic nicotine-treated mice after corneal alkali burn.	Nicotine	98-106	actin alpha 2, smooth muscle, aorta	Mus musculus	50-58