PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22243762-1	2012	In previous research, nicotine-dependent men exhibited lower putamen D2/D3 dopamine-receptor availability than non-smokers (Fehr et al.	Nicotine	22-30	dopamine receptor D3	Homo sapiens	72-92	
31078264-7	2019	Considering that D3R plays important roles in mediating reward-related physiological actions of alpha4beta2 nAChR, this study could provide a new insight into the regulatory mechanism involved in nicotine addiction.	Nicotine	196-204	dopamine receptor D3	Homo sapiens	17-20	
35455685-8	2022	The expression of the T allele of the DRD2 rs1800497 and DRD3 rs6280 polymorphisms significantly correlated with a lower level of nicotine dependence and lower use of cigarettes.	Nicotine	130-138	dopamine receptor D3	Homo sapiens	57-61	
35455685-10	2022	Concluding, DRD2 rs1800497 and DRD3 rs6280 polymorphisms are involved in nicotine dependence and cigarette smoking habits in patients with treatment-resistant mental disorders.	Nicotine	73-81	dopamine receptor D3	Homo sapiens	31-35	
18348205-0	2008	A functional polymorphism, rs6280, in DRD3 is significantly associated with nicotine dependence in European-American smokers.	Nicotine	76-84	dopamine receptor D3	Homo sapiens	38-42	
35455685-0	2022	Dopamine DRD2 and DRD3 Polymorphisms Involvement in Nicotine Dependence in Patients with Treatment-Resistant Mental Disorders.	Nicotine	52-60	dopamine receptor D3	Homo sapiens	18-22	
26279138-2	2016	We and others have proposed that targeting the dopamine D3 receptor (DRD3) may be a good strategy for treatment of nicotine dependence.	Nicotine	115-123	dopamine receptor D3	Homo sapiens	69-73	
26279138-11	2016	Our results support a role for DRD3 mediating context-induced reinstatement of nicotine seeking, but these effects may not be sustained over time.	Nicotine	79-87	dopamine receptor D3	Homo sapiens	31-35	
24927283-0	2014	Role of nicotine dependence in the association between the dopamine receptor gene DRD3 and major depressive disorder.	Nicotine	8-16	dopamine receptor D3	Homo sapiens	82-86	
24927283-12	2014	Our results further suggest that nicotine dependence may potentiate the influence of the DRD3 genetic variant on MDD.	Nicotine	33-41	dopamine receptor D3	Homo sapiens	89-93