PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35501151-9 2022 Disrupting CREB/HDAC1 interaction via either overexpression of GAL4 M1, a CREB mutant, or administration of trichostatin A, a pan-HDAC inhibitor, restored the expression levels of phospho-CREB (Ser133) and NURR1, and protected nigral dopaminergic neurons in the MPTP-treated mice brain. trichostatin A 108-122 cAMP responsive element binding protein 1 Mus musculus 11-15 35501151-9 2022 Disrupting CREB/HDAC1 interaction via either overexpression of GAL4 M1, a CREB mutant, or administration of trichostatin A, a pan-HDAC inhibitor, restored the expression levels of phospho-CREB (Ser133) and NURR1, and protected nigral dopaminergic neurons in the MPTP-treated mice brain. trichostatin A 108-122 cAMP responsive element binding protein 1 Mus musculus 188-192 16935438-6 2006 In addition, the production of ppN/OFQ mRNA is regulated by histone acetylation, also through CREB, as the histone deacetylase (HDAC) inhibitor trichostatin A increases both CREB binding to the promoter and ppN/OFQ mRNA expression. trichostatin A 144-158 cAMP responsive element binding protein 1 Mus musculus 94-98 16935438-6 2006 In addition, the production of ppN/OFQ mRNA is regulated by histone acetylation, also through CREB, as the histone deacetylase (HDAC) inhibitor trichostatin A increases both CREB binding to the promoter and ppN/OFQ mRNA expression. trichostatin A 144-158 cAMP responsive element binding protein 1 Mus musculus 174-178 23365234-8 2013 These findings suggest that post-training intra-CA1 TSA infusion promotes dynamic shift from striatum toward the hippocampal system in young but not aged animals, and support the possibility of a role for CREB in the TSA-mediated switch between these two memory systems. trichostatin A 52-55 cAMP responsive element binding protein 1 Mus musculus 205-209 22116937-6 2012 Finally, and consistent with a role of CBP in cognitive impairment in Hdh(Q7/Q111) mice, administration of the histone deacetylase inhibitor trichostatin A rescues recognition memory deficits and transcription of selective CREB/CBP target genes in Hdh(Q7/Q111) mice. trichostatin A 141-155 cAMP responsive element binding protein 1 Mus musculus 223-227 18094030-4 2008 CREB-mediated transcription as well as survival was restored by the histone deacetylase (HDAC) inhibitor trichostatine A (TSA), an effective chemotherapeutic agent. trichostatin A 105-120 cAMP responsive element binding protein 1 Mus musculus 0-4 18094030-4 2008 CREB-mediated transcription as well as survival was restored by the histone deacetylase (HDAC) inhibitor trichostatine A (TSA), an effective chemotherapeutic agent. trichostatin A 122-125 cAMP responsive element binding protein 1 Mus musculus 0-4 18094030-5 2008 Similar to severe oxidant stress, TSA-mediated survival could be abrogated by inhibition of CREB-mediated transcription. trichostatin A 34-37 cAMP responsive element binding protein 1 Mus musculus 92-96