PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30334455-6	2018	TSA treatment leads to decreased expression of CYCLIN D1, CDK4, CDK6 and BCL-XL, but increased P21 expression.	trichostatin A	0-3	BCL2 like 1	Homo sapiens	73-79	
25959059-3	2015	Here we show that TSA, a deacetylase inhibitor, reduced the ratio of Bcl-x splice variants Bcl-xL/xS in MDA-MB-231 breast cancer cells.	trichostatin A	18-21	BCL2 like 1	Homo sapiens	69-74	
25959059-3	2015	Here we show that TSA, a deacetylase inhibitor, reduced the ratio of Bcl-x splice variants Bcl-xL/xS in MDA-MB-231 breast cancer cells.	trichostatin A	18-21	BCL2 like 1	Homo sapiens	91-97	
10746741-0	2000	Trichostatin A modulates expression of p21waf1/cip1, Bcl-xL, ID1, ID2, ID3, CRAB2, GATA-2, hsp86 and TFIID/TAFII31 mRNA in human lung adenocarcinoma cells.	trichostatin A	0-14	BCL2 like 1	Homo sapiens	53-59	
22552631-6	2012	Additionally,             TSA induces expression of the pro-apoptotic protein Bax and decreases the expression             of the anti-apoptotic proteins Bcl-2 and Bcl-xL in both cell lines.	trichostatin A	26-29	BCL2 like 1	Homo sapiens	164-170	
16904634-4	2006	Combining TSA with PS-341 effectively inactivated NFkappaB signaling, downregulated the predominant endogenous anti-apoptotic factor Bcl-XL overexpression, and disrupted MAP kinase pathway.	trichostatin A	10-13	BCL2 like 1	Homo sapiens	133-139	
16009488-4	2006	The expression levels of Mcl-1 and Bcl-XL but not those of Bcl-2, Bax, and Bak were suppressed by TSA or SK-7041 treatment.	trichostatin A	98-101	BCL2 like 1	Homo sapiens	35-41	
16009488-5	2006	SK-7041 or TSA induced apoptosis and G2-M cell cycle arrest by up-regulating p21 and down-regulating cyclin B1, Mcl-1, and Bcl-XL.	trichostatin A	11-14	BCL2 like 1	Homo sapiens	123-129	
11154071-4	2000	The obtained data suggest that TSA induces pro-apoptotic genes like ID1, ID2, ID3, and down-regulates anti-apoptotic genes like Hsp27 and Bcl-xL, thereby shifting the cellular equilibrium from life to death.	trichostatin A	31-34	BCL2 like 1	Homo sapiens	138-144	
18071312-4	2008	Co-treatment, but not single treatment, with VP16 and TSA induced apoptosis in a caspase-dependent manner accompanied by a crucial decrease in Bcl-xL expression allowing Bax activation and subsequent initiation of the apoptosis inducing factor (AIF)-dependent death pathway.	trichostatin A	54-57	BCL2 like 1	Homo sapiens	143-149	
17202837-5	2006	Catalytic activation of caspase-9 and decreased expression of anti-apoptotic Bcl-2 and Bcl-XL proteins were observed in TSA-treated cells.	trichostatin A	120-123	BCL2 like 1	Homo sapiens	87-93	
16435155-6	2006	TSA treatment repressed the transcription and downregulated the expression of the antiapoptotic Bcl-2 proteins; Bcl-2 and Bcl-XL.	trichostatin A	0-3	BCL2 like 1	Homo sapiens	122-128	
16167063-6	2006	In addition, trichostatin A reduced the expression of Bcl-X(L) and cFLIP resulting in increased sensitivity to recombinant TRAIL.	trichostatin A	13-27	BCL2 like 1	Homo sapiens	54-62	
15781649-8	2005	The knockdown of the predominant Bcl-XL overexpression significantly reduces the viability of pancreatic cancer cells to TNFalpha- and TRAIL-mediated apoptosis by sublethal-dose single and combined antitumor drugs, including geldanamycin, PS-341, Trichostatin A, and doxorubicine.	trichostatin A	247-261	BCL2 like 1	Homo sapiens	33-39	
34903991-6	2021	The result indicated that zebularine and TSA changed the expression level of the Bax, Bak, Bim Bcl-2, Bcl-xL, Mcl-1, DR4, DR5, FAS, FAS-L, TRAIL, DNA methyltransferase 1, 3a, and 3b, histone deacetylase inhibitors 1, 2, and 3 by which induced cell apoptosis and inhibit cell growth in all three cell lines.	trichostatin A	41-44	BCL2 like 1	Homo sapiens	102-108