PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8761524-4 1996 Membrane cholesterol and phospholipids were positively correlated with serum HDL2. Phospholipids 25-38 junctophilin 3 Homo sapiens 77-81 10329423-4 1999 Based on phospholipid concentrations, the Kd values (0.9 x 10(-5) to 4.6 x 10(-5) M) increased in the order rHDL = HDL3 </= HDL2 < LDL while the relative reactivities (app Vmax/app Km) with LCAT were 100, 16, 1, 6%, respectively, for the different lipoproteins. Phospholipids 9-21 junctophilin 3 Homo sapiens 127-131 9589684-5 1998 Serum high-density lipoprotein phospholipids (HDL-PL) were increased in type I DM mothers because of elevated HDL2 phospholipid [0.39 mmol/L (0.27-0.48 mmol/L) compared with 0.12 mmol/L (0.06-0.21 mmol/L), respectively, P < 0.01). Phospholipids 31-43 junctophilin 3 Homo sapiens 110-114 9183494-5 1997 In SGA newborns, HDL2 and HDL3 levels were low, and HDL3 and HDL2 phospholipid and HDL2-cholesteryl ester contents were diminished. Phospholipids 66-78 junctophilin 3 Homo sapiens 61-65 9183494-5 1997 In SGA newborns, HDL2 and HDL3 levels were low, and HDL3 and HDL2 phospholipid and HDL2-cholesteryl ester contents were diminished. Phospholipids 66-78 junctophilin 3 Homo sapiens 61-65 8743899-2 1996 Hepatic lipase plays a central role in the hydrolysis of HDL2 triglycerides and phospholipids and in the concomitant apolipoprotein A-I efflux from this density class. Phospholipids 80-93 junctophilin 3 Homo sapiens 57-61 8761524-7 1996 In serum, total phospholipids and HDL2 components (cholesterol, phospholipids and protein) were higher in persons with high HDL, whereas non-esterified fatty acids (NEFA) and very low density lipoprotein (VLDL) components (triglycerides, cholesterol, phospholipids and protein) were lower. Phospholipids 64-77 junctophilin 3 Homo sapiens 34-38 8761524-7 1996 In serum, total phospholipids and HDL2 components (cholesterol, phospholipids and protein) were higher in persons with high HDL, whereas non-esterified fatty acids (NEFA) and very low density lipoprotein (VLDL) components (triglycerides, cholesterol, phospholipids and protein) were lower. Phospholipids 64-77 junctophilin 3 Homo sapiens 34-38 8280183-4 1993 HDL2 and HDL3a displayed an enrichment in surface components, phospholipids, unesterified cholesterol and apo E, leading to an increased size compared with subfractions of similar density in the controls. Phospholipids 62-75 junctophilin 3 Homo sapiens 0-4 8801866-7 1995 These directional changes in lipoprotein FC and phospholipid in the EH women significantly increased the EH FC/PC (mol/mol) ratio in their plasma, a new cardiovascular risk factor, (EH 1.08 +/- 0.22 vs. control 0.86 +/0 0.08; P < 0.01) and lowered the SPH/PC ratio HDL2 and HDL3 in EH patients of both sexes. Phospholipids 48-60 junctophilin 3 Homo sapiens 268-272 1961121-6 1991 After omega-3 supplementation, both HDL2 and HDL3 became cholesteryl ester (CE)- and TG-enriched and free cholesterol (FC)- and phospholipid (PL)-depleted. Phospholipids 128-140 junctophilin 3 Homo sapiens 36-40 1961121-6 1991 After omega-3 supplementation, both HDL2 and HDL3 became cholesteryl ester (CE)- and TG-enriched and free cholesterol (FC)- and phospholipid (PL)-depleted. Phospholipids 142-144 junctophilin 3 Homo sapiens 36-40 2242096-6 1990 As shown by density gradient ultracentrifugation, HDL2 particles that contain essentially apolipoprotein A-I, cholesterol and phospholipids represent in affected subjects the major part of HDL. Phospholipids 126-139 junctophilin 3 Homo sapiens 50-54 3168690-5 1988 In the same group, the HDL2 fraction also showed an increase in lipid (186.6 +/- 80.0 vs 77.9 +/- 21.6; P less than 0.01) and protein (133.9 +/- 60.0 vs 67.9 +/- 16.5; P less than 0.01) masses; in addition, the HDL2 percent lipid composition was different in the two patient groups, showing a decrease in esterified cholesterol (20.4 +/- 3.6 vs 25.7 +/- 2.2; P less than 0.01) and an increase in phospholipids (59.2 +/- 2.9 vs 54.8 +/- 2.6; p less than 0.01) in the Lp-X-positive group. Phospholipids 396-409 junctophilin 3 Homo sapiens 23-27 2390982-8 1990 The HDL2-subfractions had more protein, a decreased apoA-I:A-II ratio and less phospholipids in comparison to HDL2-subfractions from younger untrained and trained, and elderly trained subjects. Phospholipids 79-92 junctophilin 3 Homo sapiens 4-8 34328100-8 2021 Changes in apolipoprotein A1 (apoA-1) and PL concentrations were the most prominent in the HDL2 fraction. Phospholipids 42-44 junctophilin 3 Homo sapiens 91-95 3198064-3 1988 The analysis of lipoprotein composition, expressed as per cent of total mass demonstrates an increase of the triglyceride content in all fractions and a significant reduction of the cholesterol and phospholipid content in HDL2 particles. Phospholipids 198-210 junctophilin 3 Homo sapiens 222-226 3419323-2 1988 The mass concentrations of both low density lipoprotein (LDL) (P less than .001) and high density lipoprotein (HDL)2 (P less than .002) were reduced during acute infections due to the lowering of their cholesterol, phospholipid, and protein contents. Phospholipids 215-227 junctophilin 3 Homo sapiens 111-116 3392355-8 1988 Phospholipids (PL) were significantly reduced in HDL2 and in HDL3, but the reduction in HDL3 PL was not statistically significant. Phospholipids 0-13 junctophilin 3 Homo sapiens 49-53 3392355-8 1988 Phospholipids (PL) were significantly reduced in HDL2 and in HDL3, but the reduction in HDL3 PL was not statistically significant. Phospholipids 15-17 junctophilin 3 Homo sapiens 49-53 3544771-5 1987 Hepatic lipase has a central role in the removal of phospholipids and triglycerides from subfractions of high-density lipoprotein (HDL2) particles, but it may also function in the lipolysis of triglyceride-rich particles. Phospholipids 52-65 junctophilin 3 Homo sapiens 131-135 3126748-7 1988 Phospholipids in the HDL2-fraction and those in the HDL3-fraction of the fat-loaded cats tended to increase and decrease from 6 and 9 h after the blockade, respectively. Phospholipids 0-13 junctophilin 3 Homo sapiens 21-25 3126748-8 1988 The absolute change in HDL2 phospholipids approximated that of HDL3-phospholipids. Phospholipids 28-41 junctophilin 3 Homo sapiens 23-27 3126748-8 1988 The absolute change in HDL2 phospholipids approximated that of HDL3-phospholipids. Phospholipids 68-81 junctophilin 3 Homo sapiens 23-27 3620404-3 1987 After treatment with monophasic cyproterone acetate and biphasic desogestrel, the cholesterol and phospholipid contents of the HDL-2 fraction were significantly higher than those found after treatment with the other preparations. Phospholipids 98-110 junctophilin 3 Homo sapiens 127-132 3730408-8 1986 These HDL2-like particles were markedly enriched with cholesteryl ester but depleted of phospholipid and free cholesterol when compared with native HDL2. Phospholipids 88-100 junctophilin 3 Homo sapiens 6-10 3930554-7 1985 The reduction in HDL2b mass was associated with lower concentrations of HDL2b cholesterol, phospholipids, and apo A-I. Phospholipids 91-104 junctophilin 3 Homo sapiens 17-21 4090377-2 1985 Concentrations of cholesterol, phospholipids and apoprotein A-1 in both subfractions HDL2b and HDL2 alpha were found to alter simultaneously with the level of HDL cholesterol in blood plasma of the patients with low, normal and increased content of HDL cholesterol (10 men in each group), thus suggesting the alteration of the particles amount in both these subfractions. Phospholipids 31-44 junctophilin 3 Homo sapiens 85-89 3083830-5 1986 The changes of the HDL2 mass in women were due to significant increases of phospholipids, and both apoproteins A-I and A-II. Phospholipids 75-88 junctophilin 3 Homo sapiens 19-23 3083830-6 1986 In men, only HDL2 phospholipids rose slightly. Phospholipids 18-31 junctophilin 3 Homo sapiens 13-17 3083830-14 1986 In 4 of the 5 subjects the overall increment of the HDL2 phospholipids was larger after the phospholipid-rich emulsion than after phospholipid-poor one. Phospholipids 57-70 junctophilin 3 Homo sapiens 52-56 3083830-14 1986 In 4 of the 5 subjects the overall increment of the HDL2 phospholipids was larger after the phospholipid-rich emulsion than after phospholipid-poor one. Phospholipids 57-69 junctophilin 3 Homo sapiens 52-56 3083830-14 1986 In 4 of the 5 subjects the overall increment of the HDL2 phospholipids was larger after the phospholipid-rich emulsion than after phospholipid-poor one. Phospholipids 92-104 junctophilin 3 Homo sapiens 52-56 3705064-7 1986 In either HDL2 or HDL3, the percent content of triglyceride was higher and that of phospholipid was lower in survivors than in controls. Phospholipids 83-95 junctophilin 3 Homo sapiens 10-14 4033424-4 1985 HTGL has been postulated to be an alternate enzyme to LPL in hydrolysis of triglyceride in VLDL and to be an important enzyme for removal of phospholipid from both low-density lipoproteins (LDL) and high-density lipoproteins (HDL). Phospholipids 141-153 junctophilin 3 Homo sapiens 226-229 4024525-1 1985 In men without any symptoms of ischemic heart disease, living in two different geographical zones (Moscow and Chuckchee land) low level of high density lipoprotein (HDL) cholesterol was accompanied by alterations in phospholipid composition of HDL2 and HDL3: decrease in the ration of lecithin and increase in sphingomyelin and kephalin content. Phospholipids 216-228 junctophilin 3 Homo sapiens 244-248 7314590-1 1981 As the alpha-cholesterol concentration decreased in blood plasma of healthy men, relative content of oleic and linoleic acids was also decreased in phospholipids of HDL2 subfraction without any alterations in HDL3 fraction. Phospholipids 148-161 junctophilin 3 Homo sapiens 165-169 6667278-2 1983 The inhibitory effects were significantly higher with HDL3 than HDL2, and with HDL-without E than HDL-with E. The inhibitory effect of a phospholipid complex with apoHDL3 was higher than that with apoHDL2. Phospholipids 137-149 junctophilin 3 Homo sapiens 64-68 7046999-1 1982 Recent evidence has suggested that the major physiological substrate of the heparin-releasable (postheparin plasma) hepatic lipase is HDL2-phospholipid. Phospholipids 139-151 junctophilin 3 Homo sapiens 134-138 7298368-0 1981 Determination of cholesterol and phospholipids of HDL2, HDL3 and VHDL in patients with atherosclerosis and diabetes mellitus. Phospholipids 33-46 junctophilin 3 Homo sapiens 50-54 6794886-4 1981 In normolipidemic humans, the concentration of apo A-I and apo A-II, as well as phospholipids, increased in the light subfraction of high density lipoproteins (HDL2) 4 to 7 h after ingestion of a meal containing 1.5 g cream fat per kilogram body weight. Phospholipids 80-93 junctophilin 3 Homo sapiens 160-164 6945458-0 1981 [Determination of cholesterol and phospholipids in HDL2, HDL3 and VHDL (author"s transl)]. Phospholipids 34-47 junctophilin 3 Homo sapiens 51-55 3969013-11 1985 The increment of HDL2 concentration was due to a rise of its triglycerides, phospholipids, and apoproteins A-I and A-II but not to a rise of cholesterol. Phospholipids 76-89 junctophilin 3 Homo sapiens 17-21 3935096-6 1985 In HDL2 the percentage content of cholesterol and triglyceride decreased, while that of phospholipid increased. Phospholipids 88-100 junctophilin 3 Homo sapiens 3-7 6497946-11 1984 The major phospholipids in plasma are identical in both groups and there is an identical change under the PUFA diet, sphingomyelin is increased and phosphatidylcholine is decreased, which may be related to an increase of the HDL2/HDL3 ratio. Phospholipids 10-23 junctophilin 3 Homo sapiens 225-229 6855058-1 1983 The concentration of high density lipoproteins (HDL) and the phospholipid content of HDL2 and HDL3 were estimated in the plasma of 23 women with coronary heart disease (CHD) and in the control group of 38 healthy women. Phospholipids 61-73 junctophilin 3 Homo sapiens 85-89 7119055-5 1982 This choline-containing phospholipid monitoring method not only resolves lipoprotein peaks of the major classes (chylomicron + VLDL, LDL, HDL2 and HDL3) quantitatively, but also detects the presence of abnormal lipoproteins containing a large amount of choline-containing phospholipids. Phospholipids 24-36 junctophilin 3 Homo sapiens 138-142 7314590-2 1981 In the patients with ischemic heart disease content of linoleic acid was lower in the phospholipids and the ratio free cholesterol (HDL2 phospholipids was higher as compared with the group of healthy persons exhibiting the similar low content of cholesterol in HDL. Phospholipids 137-150 junctophilin 3 Homo sapiens 132-136 7314590-4 1981 Administration of heparin into the patients was responsible for an increase in the level of unsaturated phospholipids in HDL2 fraction (while they decreased in VLDL/as well as for a decrease in the ratio cholesterol/phospholipids. Phospholipids 104-117 junctophilin 3 Homo sapiens 121-125 7284422-1 1981 We studied the interaction of apolipoproteins A-I, C, and HDL2 with phospholipid-stabilized, triacylglycerol-rich particles to learn more about the molecular mechanisms that underlie the metabolism of chylomicrons. Phospholipids 68-80 junctophilin 3 Homo sapiens 58-62 7237831-4 1981 The HDL2 cholesterol and HDL2 phospholipid levels were negatively correlated with HDL3 protein levels. Phospholipids 30-42 junctophilin 3 Homo sapiens 25-29 7237831-8 1981 THe data are compatible with a concept proposing conversion of HDL3 to HDL2 through assimilation of cholesterol, phospholipids and apoproteins from triglyceride-rich lipoproteins during their degradation by lipoprotein lipase. Phospholipids 113-126 junctophilin 3 Homo sapiens 71-75 7193207-10 1981 The phospholipid-rich HDL2 contained a major peak (d 1.095 to 1.125 g/ml), which consisted of only spherical particles and a smaller peak (d 1.070 to 1.095 g/ml), which included a population of lipid bilayer discs. Phospholipids 4-16 junctophilin 3 Homo sapiens 22-26 28936395-7 2017 Several HDL-associated enzymes are present at elevated concentrations in HDL3 relative to large, light HDL2 and can be involved in the inactivation of short-chain oxidized phospholipids. Phospholipids 172-185 junctophilin 3 Homo sapiens 103-107 220493-4 1979 All these apoproteins spontaneously recombine with phospholipids to give stable lipid-protein complexes and freely exchange between the two major HDL subclasses, HDL2 and HDL3. Phospholipids 51-64 junctophilin 3 Homo sapiens 162-166 26773402-4 2016 METHODS: Using liquid chromatography/tandem mass spectrometry, we quantified the different species of the main phospholipids and sphingolipids in the HDL2 and HDL3 from 26 obese patients with metabolic syndrome but normal fasting glycaemia and 50 controls. Phospholipids 111-124 junctophilin 3 Homo sapiens 150-154 28207870-8 2017 The phospholipid content of HDL2 particles was a major correlate with the efflux to HDL2 (r = 0.70, p<0.001). Phospholipids 4-16 junctophilin 3 Homo sapiens 28-32 28207870-8 2017 The phospholipid content of HDL2 particles was a major correlate with the efflux to HDL2 (r = 0.70, p<0.001). Phospholipids 4-16 junctophilin 3 Homo sapiens 84-88 28207870-11 2017 The efflux to HDL2 related to the phospholipid content of HDL2 particles but the phospholipid content did not account for the impaired efflux in cardiometabolic disease, where a combination of low level and poor quality of HDL2 was observed. Phospholipids 34-46 junctophilin 3 Homo sapiens 14-18 28207870-11 2017 The efflux to HDL2 related to the phospholipid content of HDL2 particles but the phospholipid content did not account for the impaired efflux in cardiometabolic disease, where a combination of low level and poor quality of HDL2 was observed. Phospholipids 34-46 junctophilin 3 Homo sapiens 58-62 28207870-11 2017 The efflux to HDL2 related to the phospholipid content of HDL2 particles but the phospholipid content did not account for the impaired efflux in cardiometabolic disease, where a combination of low level and poor quality of HDL2 was observed. Phospholipids 34-46 junctophilin 3 Homo sapiens 58-62 24972700-8 2015 In contrast, the same exercise training program was effective in increasing contents of cholesterol, triglyceride, and phospholipid in the HDL2 subfraction in the C-TR group (p = 0.036, ES = 2.06; p = 0.038, ES = 1.77; and p = 0.0021, ES = 2.37, respectively, within-group comparisons), whereas no changes were observed in the composition of the HDL3 subfraction. Phospholipids 119-131 junctophilin 3 Homo sapiens 139-143 22419126-8 2012 ABCA1 DNA methylation levels were found negatively correlated with circulating HDL-C (r = -0.20; p = 0.05), HDL2-phospholipid levels (r = -0.43; p = 0.04), and with a trend for association with HDL peak particle size (r = -0.38; p = 0.08). Phospholipids 113-125 junctophilin 3 Homo sapiens 108-112 18498551-0 2008 HDL2 of heavy alcohol drinkers enhances cholesterol efflux from raw macrophages via phospholipid-rich HDL 2b particles. Phospholipids 84-96 junctophilin 3 Homo sapiens 0-4 18498551-0 2008 HDL2 of heavy alcohol drinkers enhances cholesterol efflux from raw macrophages via phospholipid-rich HDL 2b particles. Phospholipids 84-96 junctophilin 3 Homo sapiens 102-107