PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33713163-11	2021	LiCl, a Wnt/beta-catenin signaling activator, was observed to reverse the protective effect of RTEF-1 overexpression on VSMCs calcification induced by beta-GP.	Lithium Chloride	0-4	Wnt family member 3A	Homo sapiens	8-11	
25359619-6	2014	We report here that Wnt activation by beta-catenin/T cell factor 4 (TCF4) over-expression or lithium chloride (LiCl) treatment increased Gli2 and PTHrP expression in osteolytic cancer cells.	Lithium Chloride	111-115	Wnt family member 3A	Homo sapiens	20-23	
22134133-6	2012	Interestingly, activation of the canonical Wnt-signaling pathway via Wnt3a or lithium chloride reverted the suppressive effect of TCDD on beta-catenin and E-cadherin expressions in the BeWo and RL95-2 cells, and restored the spheroids attachment rate to be comparable to the untreated controls.	Lithium Chloride	78-94	Wnt family member 3A	Homo sapiens	43-46	
32232394-13	2020	Activation of Wnt/beta-catenin pathway by LiCl abolished the effects of si-TRIM31 on cell proliferation, apoptosis and sensitivity to daunorubicin in AML cells.	Lithium Chloride	42-46	Wnt family member 3A	Homo sapiens	14-17	
29659176-4	2018	Here we showed that treatment with a Wnt pathway activator (LiCl) reduced elastase-induced airspace enlargement and cigarette smoke extract (CSE)-induced lung inflammatory responses in WT mice, which was associated with increased activation of Nrf2 pathway.	Lithium Chloride	60-64	Wnt family member 3A	Homo sapiens	37-40	
29120400-5	2017	Also, OCCM30-fibrin expressed biomineralization-associated markers at higher levels than OCCM30-TCD, of which levels were further increased with LiCl, a Wnt signaling activator.	Lithium Chloride	145-149	Wnt family member 3A	Homo sapiens	153-156	
29120400-7	2017	Activation of canonical Wnt signaling with LiCl treatment or with forced lymphoid enhancer factor 1 (LEF1)-expression increased the expression of plasminogen.	Lithium Chloride	43-47	Wnt family member 3A	Homo sapiens	24-27	
26271413-8	2015	Moreover, by the of engagement of Wnt pathway agonist (LiCl) and antagonist (ICG 001) we demonstrate that DOX-TRF conjugate effectively reduces transcription of key genes involved in beta-catenin signaling transduction trial (Wnt3a, DVL-1, FZD-3, LRP5, beta-catenin, DKK2) and triggers morphology alternations of CML cells.	Lithium Chloride	55-59	Wnt family member 3A	Homo sapiens	34-37	
22854964-6	2012	Transient activation of the Wnt/beta-catenin pathway either by transfection of a constitutively active form of beta-catenin or by LiCl or Wnt-3a conditioned medium treatment induced hTERT mRNA expression and elevated TA in different cell lines.	Lithium Chloride	130-134	Wnt family member 3A	Homo sapiens	28-31	
31873116-5	2019	In contrast, activation of Wnt signaling using exogenous Wnt ligand (Wnt3a) or LiCl (GSK3 inhibitor) improved the BBB phenotypes of the hCMEC/D3 culture model, resulting in reduced paracellular permeability, and increased P-glycoprotein (P-gp) and breast cancer resistance associated protein (BCRP) efflux transporter activity.	Lithium Chloride	79-83	Wnt family member 3A	Homo sapiens	27-30	
28347817-4	2017	Meanwhile, activation Wnt3a/beta-catenin signal with exogenous Wnt3alpha protein (100 ng/ml) or Lithium Chloride (LiCl, 4 mM) decreased significantly apoptosis of BMECs induced by OGD with increasing expression of Bcl-2 in the whole cell and beta-catenin in the nucleus.	Lithium Chloride	96-112	Wnt family member 3A	Homo sapiens	22-27	
28347817-4	2017	Meanwhile, activation Wnt3a/beta-catenin signal with exogenous Wnt3alpha protein (100 ng/ml) or Lithium Chloride (LiCl, 4 mM) decreased significantly apoptosis of BMECs induced by OGD with increasing expression of Bcl-2 in the whole cell and beta-catenin in the nucleus.	Lithium Chloride	114-118	Wnt family member 3A	Homo sapiens	22-27	
20693288-4	2010	Treatment of cells with a Wnt activator, lithium chloride, up-regulated DPAGT1 transcript levels that correlated with an increase in the beta-catenin abundance.	Lithium Chloride	41-57	Wnt family member 3A	Homo sapiens	26-29	
21501658-7	2011	LiCl-induced Wnt transactivation was suppressed by addition of metformin.	Lithium Chloride	0-4	Wnt family member 3A	Homo sapiens	13-16	
21501658-6	2011	Transactivation by Wnt was potentiated by inhibiting beta-catenin degradation with lithium chloride (LiCl).	Lithium Chloride	83-99	Wnt family member 3A	Homo sapiens	19-22	
21501658-6	2011	Transactivation by Wnt was potentiated by inhibiting beta-catenin degradation with lithium chloride (LiCl).	Lithium Chloride	101-105	Wnt family member 3A	Homo sapiens	19-22