PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22134133-6 2012 Interestingly, activation of the canonical Wnt-signaling pathway via Wnt3a or lithium chloride reverted the suppressive effect of TCDD on beta-catenin and E-cadherin expressions in the BeWo and RL95-2 cells, and restored the spheroids attachment rate to be comparable to the untreated controls. Lithium Chloride 78-94 Wnt family member 3A Homo sapiens 43-46 22854964-6 2012 Transient activation of the Wnt/beta-catenin pathway either by transfection of a constitutively active form of beta-catenin or by LiCl or Wnt-3a conditioned medium treatment induced hTERT mRNA expression and elevated TA in different cell lines. Lithium Chloride 130-134 Wnt family member 3A Homo sapiens 28-31 21501658-7 2011 LiCl-induced Wnt transactivation was suppressed by addition of metformin. Lithium Chloride 0-4 Wnt family member 3A Homo sapiens 13-16 21501658-6 2011 Transactivation by Wnt was potentiated by inhibiting beta-catenin degradation with lithium chloride (LiCl). Lithium Chloride 83-99 Wnt family member 3A Homo sapiens 19-22 21501658-6 2011 Transactivation by Wnt was potentiated by inhibiting beta-catenin degradation with lithium chloride (LiCl). Lithium Chloride 101-105 Wnt family member 3A Homo sapiens 19-22 25359619-6 2014 We report here that Wnt activation by beta-catenin/T cell factor 4 (TCF4) over-expression or lithium chloride (LiCl) treatment increased Gli2 and PTHrP expression in osteolytic cancer cells. Lithium Chloride 111-115 Wnt family member 3A Homo sapiens 20-23 20693288-4 2010 Treatment of cells with a Wnt activator, lithium chloride, up-regulated DPAGT1 transcript levels that correlated with an increase in the beta-catenin abundance. Lithium Chloride 41-57 Wnt family member 3A Homo sapiens 26-29 31873116-5 2019 In contrast, activation of Wnt signaling using exogenous Wnt ligand (Wnt3a) or LiCl (GSK3 inhibitor) improved the BBB phenotypes of the hCMEC/D3 culture model, resulting in reduced paracellular permeability, and increased P-glycoprotein (P-gp) and breast cancer resistance associated protein (BCRP) efflux transporter activity. Lithium Chloride 79-83 Wnt family member 3A Homo sapiens 27-30 33713163-11 2021 LiCl, a Wnt/beta-catenin signaling activator, was observed to reverse the protective effect of RTEF-1 overexpression on VSMCs calcification induced by beta-GP. Lithium Chloride 0-4 Wnt family member 3A Homo sapiens 8-11 32232394-13 2020 Activation of Wnt/beta-catenin pathway by LiCl abolished the effects of si-TRIM31 on cell proliferation, apoptosis and sensitivity to daunorubicin in AML cells. Lithium Chloride 42-46 Wnt family member 3A Homo sapiens 14-17 29659176-4 2018 Here we showed that treatment with a Wnt pathway activator (LiCl) reduced elastase-induced airspace enlargement and cigarette smoke extract (CSE)-induced lung inflammatory responses in WT mice, which was associated with increased activation of Nrf2 pathway. Lithium Chloride 60-64 Wnt family member 3A Homo sapiens 37-40 29120400-5 2017 Also, OCCM30-fibrin expressed biomineralization-associated markers at higher levels than OCCM30-TCD, of which levels were further increased with LiCl, a Wnt signaling activator. Lithium Chloride 145-149 Wnt family member 3A Homo sapiens 153-156 29120400-7 2017 Activation of canonical Wnt signaling with LiCl treatment or with forced lymphoid enhancer factor 1 (LEF1)-expression increased the expression of plasminogen. Lithium Chloride 43-47 Wnt family member 3A Homo sapiens 24-27 28347817-4 2017 Meanwhile, activation Wnt3a/beta-catenin signal with exogenous Wnt3alpha protein (100 ng/ml) or Lithium Chloride (LiCl, 4 mM) decreased significantly apoptosis of BMECs induced by OGD with increasing expression of Bcl-2 in the whole cell and beta-catenin in the nucleus. Lithium Chloride 96-112 Wnt family member 3A Homo sapiens 22-27 28347817-4 2017 Meanwhile, activation Wnt3a/beta-catenin signal with exogenous Wnt3alpha protein (100 ng/ml) or Lithium Chloride (LiCl, 4 mM) decreased significantly apoptosis of BMECs induced by OGD with increasing expression of Bcl-2 in the whole cell and beta-catenin in the nucleus. Lithium Chloride 114-118 Wnt family member 3A Homo sapiens 22-27 26271413-8 2015 Moreover, by the of engagement of Wnt pathway agonist (LiCl) and antagonist (ICG 001) we demonstrate that DOX-TRF conjugate effectively reduces transcription of key genes involved in beta-catenin signaling transduction trial (Wnt3a, DVL-1, FZD-3, LRP5, beta-catenin, DKK2) and triggers morphology alternations of CML cells. Lithium Chloride 55-59 Wnt family member 3A Homo sapiens 34-37