PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29421570-2 2018 The molecular hybridization approach was based on the combination, in a single molecule, of the pharmacophoric N-benzyl-piperidine subunit of donepezil, the substituted hydroxy-piperidine fragment of the AChE inhibitor LASSBio-767, and an acylhydrazone linker, a privileged structure present in a number of synthetic aryl- and aryl-acylhydrazone derivatives with significant AChE and anti-inflammatory activities. hydroxy-piperidine 169-187 acetylcholinesterase (Cartwright blood group) Homo sapiens 204-208