PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35370661-3 2022 Here, we report that the natural sesquiterpene lactone alantolactone (ALA) was shown to bind directly to AKR1C1 through the Proteome Integral Solubility Alteration (PISA) analysis, a label-free target identification approach based on thermal proteome profiling. sesquiterpene lactone 33-54 aldo-keto reductase family 1 member C1 Homo sapiens 105-111