PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28441337-0 2017 A Study of the Differential Effects of Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) on Gene Expression Profiles of Stimulated Thp-1 Macrophages. Eicosapentaenoic Acid 39-60 GLI family zinc finger 2 Homo sapiens 140-145 29078847-15 2017 CONCLUSIONS: The present results suggest that resveratrol and EPA, but not DHA, markedly activated the SIRT1 gene expression in THP1 cells, and that high glucose medium could inhibit the basic gene expression, but not powerful resveratrol-induced gene expression, in those cells. Eicosapentaenoic Acid 62-65 GLI family zinc finger 2 Homo sapiens 128-132 28441337-6 2017 Conclusions: EPA and DHA appear to exert differential effects on gene expression in THP-1 macrophages. Eicosapentaenoic Acid 13-16 GLI family zinc finger 2 Homo sapiens 84-89 28441337-0 2017 A Study of the Differential Effects of Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) on Gene Expression Profiles of Stimulated Thp-1 Macrophages. Eicosapentaenoic Acid 62-65 GLI family zinc finger 2 Homo sapiens 140-145 28441337-3 2017 The aim of the present study was to characterize gene expression profiles of THP-1 macrophages, incubated in either EPA or DHA and stimulated with lipopolysaccharide (LPS), a pro-inflammatory agent. Eicosapentaenoic Acid 116-119 GLI family zinc finger 2 Homo sapiens 77-82 24396573-4 2013 Alpha Linolenic Acid (LA), and Eicosapentaenoic Acid (EPA) on the PPARalpha and ACAT1 mRNA expression by Real time PCR and cholesterol homeostasis in THP-1 macrophages derived foam cells. Eicosapentaenoic Acid 31-52 GLI family zinc finger 2 Homo sapiens 150-155 25631736-4 2015 Our results showed that n-3 PUFAs docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) remarkably attenuated the adhesion of THP-1 cells to HAECs, probably through inhibiting the expression of VCAM-1 and ICAM-1. Eicosapentaenoic Acid 65-86 GLI family zinc finger 2 Homo sapiens 131-136 25631736-4 2015 Our results showed that n-3 PUFAs docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) remarkably attenuated the adhesion of THP-1 cells to HAECs, probably through inhibiting the expression of VCAM-1 and ICAM-1. Eicosapentaenoic Acid 88-91 GLI family zinc finger 2 Homo sapiens 131-136 24901717-0 2014 Effect of eicosapentaenoic acid on the expression of ABCG1 gene in the human monocyte THP-1 cells. Eicosapentaenoic Acid 10-31 GLI family zinc finger 2 Homo sapiens 86-91 24901717-8 2014 The objective of this study was to evaluate the effect of different concentrations of EPA on the expression of ABCG1 gene in the human monocyte THP-1 cells. Eicosapentaenoic Acid 86-89 GLI family zinc finger 2 Homo sapiens 144-149 25860776-7 2015 Thus our data indicate that THP-1 macrophages prominently utilize EPA and DHA for monohydroxylated metabolite formation, in particular 18-HEPE, which has been shown to be released by macrophages to prevent pressure overload-induced maladaptive cardiac remodeling. Eicosapentaenoic Acid 66-69 GLI family zinc finger 2 Homo sapiens 28-33 24396573-4 2013 Alpha Linolenic Acid (LA), and Eicosapentaenoic Acid (EPA) on the PPARalpha and ACAT1 mRNA expression by Real time PCR and cholesterol homeostasis in THP-1 macrophages derived foam cells. Eicosapentaenoic Acid 54-57 GLI family zinc finger 2 Homo sapiens 150-155 20112284-7 2010 In addition, pretreatment with ecosapentaenoic acid (EPA), a substrate competitor of arachidonic acid (AA), also blocked LPS-induced VCAM-1 mRNA and protein expression, and THP-1 adherence. Eicosapentaenoic Acid 53-56 GLI family zinc finger 2 Homo sapiens 173-178 10751643-0 2000 Modulation of PAF production by incorporation of arachidonic acid and eicosapentaenoic acid in phospholipids of human leukemic monocyte-like cells THP-1. Eicosapentaenoic Acid 70-91 GLI family zinc finger 2 Homo sapiens 147-152 10751643-4 2000 Supplementation of THP-1 with AA (25 microM, 1 week) or EPA (25 microM, 1 week) led to their efficient incorporation, in comparable quantities and with similar distributions, into phosphatidylcholine and phosphatidylethanolamine, and to a lesser extent into phosphatidylinositol. Eicosapentaenoic Acid 56-59 GLI family zinc finger 2 Homo sapiens 19-24 10751643-5 2000 THP-1 cells supplemented with AA or with EPA synthetized similar amounts of PAF and of acyl analog of PAF under resting condition. Eicosapentaenoic Acid 41-44 GLI family zinc finger 2 Homo sapiens 0-5 23433401-0 2013 Eicosapentaenoic acid suppresses palmitate-induced cytokine production by modulating long-chain acyl-CoA synthetase 1 expression in human THP-1 macrophages. Eicosapentaenoic Acid 0-21 GLI family zinc finger 2 Homo sapiens 138-143 16781858-4 2007 Pretreatment with 100 microM EPA and DHA significantly decreased lipopolysaccharide (LPS)-stimulated THP-1 macrophage tumor necrosis factor (TNF) alpha, interleukin (IL) 1beta and IL-6 production (P<.02), compared to control cells. Eicosapentaenoic Acid 29-32 GLI family zinc finger 2 Homo sapiens 101-106 16781858-8 2007 Both EPA and DHA down-regulated LPS-induced NF-kappaB/DNA binding in THP-1 macrophages by approximately 13% (P< or =.03). Eicosapentaenoic Acid 5-8 GLI family zinc finger 2 Homo sapiens 69-74 34332075-0 2021 Eicosapentaenoic acid membrane incorporation stimulates ABCA1-mediated cholesterol efflux from human THP-1 macrophages. Eicosapentaenoic Acid 0-21 GLI family zinc finger 2 Homo sapiens 101-106