PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23680128-0	2013	Oxidized eicosapentaenoic acids more potently reduce LXRalpha-induced cellular triacylglycerol via suppression of SREBP-1c, PGC-1beta and GPA than its intact form.	Eicosapentaenoic Acid	9-31	sterol regulatory element binding transcription factor 1	Homo sapiens	114-122	
25264165-6	2014	Polyunsaturated docosahexaenoic acid (DHA, C22:6), eicosapentaenoic acid (EPA, C20:5) and arachidonic acid (AA, C20:4) were able to reduce SREBP-1 binding to SCD1 promoter, while saturated stearic acid (SA, C18:0) did not give any effect.	Eicosapentaenoic Acid	51-72	sterol regulatory element binding transcription factor 1	Homo sapiens	139-146	
34670012-2	2022	We have found that polyunsaturated fatty acid eicosapentaenoic acid (EPA) downregulates Selenop expression by inactivating SREBP-1c.	Eicosapentaenoic Acid	69-72	sterol regulatory element binding transcription factor 1	Homo sapiens	123-131	
17005995-0	2006	Trans geometric isomers of EPA decrease LXRalpha-induced cellular triacylglycerol via suppression of SREBP-1c and PGC-1beta.	Eicosapentaenoic Acid	27-30	sterol regulatory element binding transcription factor 1	Homo sapiens	101-109	
17005995-7	2006	We found that TEPA, but not EPA, decreased the mRNA expression of peroxisome proliferator-activated receptor gamma coactivator 1beta (PGC-1beta), which is a coactivator of both LXRalpha and SREBP-1.	Eicosapentaenoic Acid	15-18	sterol regulatory element binding transcription factor 1	Homo sapiens	190-197	
15473864-9	2005	Moreover, a lower nuclear availability of both SREBP-1 and SREBP-2 mature forms was observed in HepG2 human hepatoblastoma cells treated with arachidonate, EPA or DHA.	Eicosapentaenoic Acid	156-159	sterol regulatory element binding transcription factor 1	Homo sapiens	47-54	
11694526-5	2002	The luciferase activities of both SREBP-1c promoter and LXRE enhancer constructs induced by co-expression of LXRalpha or -beta were strongly suppressed by the addition of various PUFAs (arachidonic acid > eicosapentaenoic acid > docosahexaenoic acid > linoleic acid), whereas saturated or mono-unsaturated fatty acids had minimal effects.	Eicosapentaenoic Acid	208-229	sterol regulatory element binding transcription factor 1	Homo sapiens	34-42	
34670012-2	2022	We have found that polyunsaturated fatty acid eicosapentaenoic acid (EPA) downregulates Selenop expression by inactivating SREBP-1c.	Eicosapentaenoic Acid	46-67	sterol regulatory element binding transcription factor 1	Homo sapiens	123-131	
34532024-9	2021	The cellular lipid droplets, TG content, and the expression of ACC (by 75%) and SREBP-1c (by 45%) were increased by OA stimulation (p < .05), which was inhibited by EPA treatment.	Eicosapentaenoic Acid	165-168	sterol regulatory element binding transcription factor 1	Homo sapiens	80-88	
34532024-10	2021	However, the effect of EPA treatment was abolished when SREBP-1c was silenced.	Eicosapentaenoic Acid	23-26	sterol regulatory element binding transcription factor 1	Homo sapiens	56-64	
29463265-6	2018	EPA and DHA inhibited cholesterol absorption in Caco-2 monolayer might be caused by down-regulating NPC1L1 mRNA and protein levels, which were associated with inhibition of SREBP-1/- 2 mRNA expression levels.	Eicosapentaenoic Acid	0-3	sterol regulatory element binding transcription factor 1	Homo sapiens	173-184