PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
3035097-9	1987	Competition curves for the binding of unlabeled DN-1417 to limbic forebrain and lumbosacral spinal cord ([3H]TRH as assay ligand) were monophasic (not biphasic like those of Funatsu et al.)	dn	48-50	thyrotropin releasing hormone	Rattus norvegicus	109-112	
2989427-7	1985	Experiments using DN-1417 (gamma-butyrolactone-gamma-carbonyl-histidyl-prolinamide citrate), a synthetic TRH analogue with a more potent central activity, indicated the presence of TRH receptors having a high affinity to DN-1417 at least in the limbic forebrain but not in the pituitary.	dn	18-20	thyrotropin releasing hormone	Rattus norvegicus	105-108	
2989427-7	1985	Experiments using DN-1417 (gamma-butyrolactone-gamma-carbonyl-histidyl-prolinamide citrate), a synthetic TRH analogue with a more potent central activity, indicated the presence of TRH receptors having a high affinity to DN-1417 at least in the limbic forebrain but not in the pituitary.	dn	18-20	thyrotropin releasing hormone	Rattus norvegicus	181-184	
3928465-0	1985	[A TRH analog (DN-1417).	dn	15-17	thyrotropin releasing hormone	Rattus norvegicus	3-6	
3081836-1	1986	The effects of a recently synthesized analogue, thyrotropin-releasing hormone (TRH) analogue, DN-1417, on evoked responses and long-term potentiation (LTP) of the perforant path input to the dentate gyrus were examined in normal rats and after hypophysectomy.	dn	94-96	thyrotropin releasing hormone	Rattus norvegicus	48-77	
3081836-1	1986	The effects of a recently synthesized analogue, thyrotropin-releasing hormone (TRH) analogue, DN-1417, on evoked responses and long-term potentiation (LTP) of the perforant path input to the dentate gyrus were examined in normal rats and after hypophysectomy.	dn	94-96	thyrotropin releasing hormone	Rattus norvegicus	79-82	
2869169-10	1985	(5) [3H]-TRH binding: The addition of 10(-6) to 10(-4) M of DN-1417 and TRH inhibited concentration-dependently [3H]-TRH binding in the nucleus accumbens and striatal slices.	dn	60-62	thyrotropin releasing hormone	Rattus norvegicus	9-12	
3928869-5	1985	Dose-proportional transfer of DN-1417 through the everted small intestine was also found within the concentration range from 120 ng/ml to 27 mg/ml, whereas the transfer ratio of TRH decreased with increase in the concentration of TRH.	dn	30-32	thyrotropin releasing hormone	Rattus norvegicus	178-181	
3928869-5	1985	Dose-proportional transfer of DN-1417 through the everted small intestine was also found within the concentration range from 120 ng/ml to 27 mg/ml, whereas the transfer ratio of TRH decreased with increase in the concentration of TRH.	dn	30-32	thyrotropin releasing hormone	Rattus norvegicus	230-233	
3924795-0	1985	[A TRH analog (DN-1417).	dn	15-17	thyrotropin releasing hormone	Rattus norvegicus	3-6	
3924797-0	1985	[A TRH analog (DN-1417).	dn	15-17	thyrotropin releasing hormone	Rattus norvegicus	3-6	
6428117-3	1984	The potency of DN-1417 related to TSH release was 0.14-0.26% that of TRH.	dn	15-17	thyrotropin releasing hormone	Rattus norvegicus	69-72	
6139495-11	1983	alpha-Methyl-p-tyrosine (alpha-MT, 250 mg/kg i.p., 4 hr before), a tyrosine hydroxylase inhibitor, almost completely blocked DN-1417- and MAP-induced increases in cyclic nucleotides, slightly blocked TRH-effects, and had no effect on Apo-effects.	dn	125-127	thyrotropin releasing hormone	Rattus norvegicus	200-203	
6413736-0	1983	A TRH analog (DN-1417): effects on local cerebral glucose utilization in conscious and pentobarbitalized rats determined by the autoradiographic 2-deoxy-[14C]glucose method.	dn	14-16	thyrotropin releasing hormone	Rattus norvegicus	2-5	
6410685-4	1983	DN 1417, a potent analogue of TRH with a very low TSH (thyroid stimulating hormone) releasing activity was more effective in stimulating respiratory frequency, while TRH-OH, regarded to have neither TSH releasing nor extra hypothalamic effects, at equimolar doses was unable to induce any changes in the respiratory pattern.	dn	0-2	thyrotropin releasing hormone	Rattus norvegicus	30-33