PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16112505-7 2005 The inhibition of MEK induced a stronger reduction of proliferation rate in fibroblasts from patients with (0.079+/-0.006x10(5) cells day(-1); 55% of reduction) than without DN (0.068+/-0.006; 38% of reduction) and in nondiabetic participants (0.064+/-0.006; 32% of reduction), and differences among groups were lost. dn 174-176 mitogen-activated protein kinase kinase 7 Homo sapiens 18-21 16112505-8 2005 In parallel, PD 098059 induced a greater reduction of MEK-dependent phosphorylation in lysates of fibroblasts from patients with (73%) than without (40%) DN. dn 154-156 mitogen-activated protein kinase kinase 7 Homo sapiens 54-57