PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21159975-4	2010	In contrast, in amphetamine- and cocaine-preexposed mice, an amphetamine or cocaine challenge no longer activates CREB unless Ca(v)1.2 LTCCs are blocked.	Amphetamine	16-27	cAMP responsive element binding protein 1	Mus musculus	114-118	
21159975-4	2010	In contrast, in amphetamine- and cocaine-preexposed mice, an amphetamine or cocaine challenge no longer activates CREB unless Ca(v)1.2 LTCCs are blocked.	Amphetamine	61-72	cAMP responsive element binding protein 1	Mus musculus	114-118	
18848971-5	2008	Furthermore, co-administration of BA or VPA with amphetamine produced additive effects on histone H4 acetylation as well as CREB phosphorylation in the striatum.	Amphetamine	49-60	cAMP responsive element binding protein 1	Mus musculus	124-128	
19902350-7	2010	The GraL GAD(67) level may be regulated by the activation of CREB, as the phosphorylated (p) CREB coexisted with GAD(67), and the percentage of GAD(67)-expressing pCREB neurons was decreased by the amphetamine exposure.	Amphetamine	198-209	cAMP responsive element binding protein 1	Mus musculus	61-65	
19830406-7	2010	Basal expression of p-CREB (but not BDNF) was higher in D (1) (-/-) than D (1) (+/+) mice and was reduced after amphetamine treatment.	Amphetamine	112-123	cAMP responsive element binding protein 1	Mus musculus	22-26	
19059431-8	2009	In the granule somata, Amph probably inhibits expression of GAD67 by decreasing phosphorylation of CREB (pCREB).	Amphetamine	23-27	cAMP responsive element binding protein 1	Mus musculus	99-103	
18848971-0	2008	Additive effects of histone deacetylase inhibitors and amphetamine on histone H4 acetylation, cAMP responsive element binding protein phosphorylation and DeltaFosB expression in the striatum and locomotor sensitization in mice.	Amphetamine	55-66	cAMP responsive element binding protein 1	Mus musculus	94-133	
18848971-4	2008	Conversely, repeated treatment with BA or VPA produced amphetamine-like effects: enhanced cAMP responsive element binding protein (CREB) phosphorylation at Ser(133) position and increased DeltaFosB protein levels in the striatum.	Amphetamine	55-66	cAMP responsive element binding protein 1	Mus musculus	90-129	
18848971-7	2008	Finally, the additive effect of VPA/BA and amphetamine on histone H4 acetylation, phosphorylated CREB, and DeltaFosB was associated with potentiated amphetamine-induced locomotor activity.	Amphetamine	43-54	cAMP responsive element binding protein 1	Mus musculus	97-101	
12557267-1	2003	Previous work has demonstrated that acute and chronic administration of amphetamine causes phosphorylation of the transcription factor CREB, the cAMP response element (CRE) binding protein, in striatum, a brain region important for the behavioral actions of the drug.	Amphetamine	72-83	cAMP responsive element binding protein 1	Mus musculus	135-139	
16983645-0	2006	Differential effects of chronic amphetamine and baclofen administration on cAMP levels and phosphorylation of CREB in distinct brain regions of wild type and monoamine oxidase B-deficient mice.	Amphetamine	32-43	cAMP responsive element binding protein 1	Mus musculus	110-114	
16983645-5	2006	After the last treatment, levels of cAMP and phosphorylated (p) cyclic-AMP response element binding protein (CREB) were up-regulated in the striatum and somatosensory cortex of Amph-treated WT mice, while similar to the saline-controls in the baclofen+Amph-treated group, indicating the blockade by baclofen to Amph.	Amphetamine	177-181	cAMP responsive element binding protein 1	Mus musculus	64-107	
16983645-5	2006	After the last treatment, levels of cAMP and phosphorylated (p) cyclic-AMP response element binding protein (CREB) were up-regulated in the striatum and somatosensory cortex of Amph-treated WT mice, while similar to the saline-controls in the baclofen+Amph-treated group, indicating the blockade by baclofen to Amph.	Amphetamine	177-181	cAMP responsive element binding protein 1	Mus musculus	109-113	
16983645-5	2006	After the last treatment, levels of cAMP and phosphorylated (p) cyclic-AMP response element binding protein (CREB) were up-regulated in the striatum and somatosensory cortex of Amph-treated WT mice, while similar to the saline-controls in the baclofen+Amph-treated group, indicating the blockade by baclofen to Amph.	Amphetamine	252-256	cAMP responsive element binding protein 1	Mus musculus	109-113	
16983645-5	2006	After the last treatment, levels of cAMP and phosphorylated (p) cyclic-AMP response element binding protein (CREB) were up-regulated in the striatum and somatosensory cortex of Amph-treated WT mice, while similar to the saline-controls in the baclofen+Amph-treated group, indicating the blockade by baclofen to Amph.	Amphetamine	252-256	cAMP responsive element binding protein 1	Mus musculus	109-113