PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19926806-9	2009	By contrast, TH protein levels were rhythmic in both the NAcc and VTA, but the peaks differed with that in the NAcc coinciding with the peak of sex reward and that in the VTA associated with the peak in amphetamine reward.	Amphetamine	203-214	tyrosine hydroxylase	Rattus norvegicus	13-15	
28750831-0	2017	Potential role of tyrosine hydroxylase in the loss of psychostimulant effect of amphetamine under conditions of impaired dopamine transporter activity.	Amphetamine	80-91	tyrosine hydroxylase	Rattus norvegicus	18-38	
28750831-6	2017	Changes in TH activity, assessed as L-DOPA accumulation and TH phosphorylation levels, were measured in amphetamine treated rats with or without pretreatment with GBR12909.	Amphetamine	104-115	tyrosine hydroxylase	Rattus norvegicus	11-13	
28750831-8	2017	GBR12909, while having no effect on its own, blocked amphetamine-induced elevation of TH activity in dorsal striatum and nucleus accumbens, measured as increased tissue L-DOPA concentration.	Amphetamine	53-64	tyrosine hydroxylase	Rattus norvegicus	86-88	
28750831-10	2017	Our findings indicate that other mechanisms than phosphorylation-regulated TH activity changes are responsible for the paradoxical calming effect of amphetamine under conditions of impaired DAT activity.	Amphetamine	149-160	tyrosine hydroxylase	Rattus norvegicus	75-77	
19926806-11	2009	The phase relationships between reward rhythms and mesolimbic TH protein levels suggest that an increased capacity for the release of dopamine in the NAcc may underlie the rhythms in sex-related reward, while amphetamine-related reward occurs at a time when the likelihood of evoked NAcc DA release is relatively low.	Amphetamine	209-220	tyrosine hydroxylase	Rattus norvegicus	62-64	
16708545-7	2006	A marked improvement in amphetamine-induced turning behavior was observed in parkinsonian rats implanted with F3.TH.GTPCH cells, but not in control rats receiving F3 NSC.	Amphetamine	24-35	tyrosine hydroxylase	Rattus norvegicus	113-115	
19499701-10	2009	With this approach no more than 100 surviving TH-positive neurons are necessary to produce functional effects in the amphetamine-induced rotation test.	Amphetamine	117-128	tyrosine hydroxylase	Rattus norvegicus	46-48	
9694971-0	1998	Long-term effects of amphetamine neurotoxicity on tyrosine hydroxylase mRNA and protein in aged rats.	Amphetamine	21-32	tyrosine hydroxylase	Rattus norvegicus	50-70	
15836913-6	2005	The repeated administration of dl-amphetamine resulted in a decrease of tyrosine hydroxylase (TH) immunostaining in the caudate putamen, hyperthermia, and anxiety-like behavioural changes.	Amphetamine	31-45	tyrosine hydroxylase	Rattus norvegicus	72-92	
11954043-6	2002	During the first 3 weeks after simultaneous lesion and implantation, the amphetamine-induced rotating behavior of GDNF-treated rats was improved compared to controls and an increase in TH expression (+26%) was measured in the striatum 6 weeks after lesion.	Amphetamine	73-84	tyrosine hydroxylase	Rattus norvegicus	185-187	
9694971-1	1998	Four injections (intraperitoneal) of 3 mg/kg amphetamine (2 hr apart) produced pronounced hyperthermia and sustained decreases in dopamine levels and tyrosine hydroxylase (TH) protein levels in the striatum of 15-month-old male rats.	Amphetamine	45-56	tyrosine hydroxylase	Rattus norvegicus	150-170	
9694971-1	1998	Four injections (intraperitoneal) of 3 mg/kg amphetamine (2 hr apart) produced pronounced hyperthermia and sustained decreases in dopamine levels and tyrosine hydroxylase (TH) protein levels in the striatum of 15-month-old male rats.	Amphetamine	45-56	tyrosine hydroxylase	Rattus norvegicus	172-174	
9694971-5	1998	Interestingly, TH-immunopositive cell bodies were observed 4 months after amphetamine in the lateral caudate/putamen, defined anteriorly by the genu of the corpus collosum and posteriorly by the junction of the anterior commissures; these striatal TH-positive cells were not observed in saline- or amphetamine-treated rats that did not become hyperthermic.	Amphetamine	74-85	tyrosine hydroxylase	Rattus norvegicus	15-17	
9694971-5	1998	Interestingly, TH-immunopositive cell bodies were observed 4 months after amphetamine in the lateral caudate/putamen, defined anteriorly by the genu of the corpus collosum and posteriorly by the junction of the anterior commissures; these striatal TH-positive cells were not observed in saline- or amphetamine-treated rats that did not become hyperthermic.	Amphetamine	298-309	tyrosine hydroxylase	Rattus norvegicus	15-17	
9694971-6	1998	In addition, low levels (orders of magnitude lower than that present in the midbrain) of TH mRNA were detected using reverse transcription-polymerase chain reaction in the striatum of these amphetamine-treated rats.	Amphetamine	190-201	tyrosine hydroxylase	Rattus norvegicus	89-91	
9171157-9	1997	In summary, selective dissection of the embryonic ventral mesencephalon is possible, functional recovery as assessed by amphetamine-induced rotation in animals transplanted with MVM is similar to that seen in animals grafted with VM, and AHD/TH neurons have a selective reinnervation pattern in the PD transplantation paradigm.	Amphetamine	120-131	tyrosine hydroxylase	Rattus norvegicus	242-244	
7873126-0	1994	Repeated amphetamine evokes biphasic alterations in the tyrosine hydroxylase mRNA level in the rat adrenal medulla: an in situ hybridization study.	Amphetamine	9-20	tyrosine hydroxylase	Rattus norvegicus	56-76