PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17658665-1 2007 Mice lacking the PACAP gene (PACAP(-/-)) display psychomotor abnormalities such as novelty-induced hyperactivity and jumping behavior, and they show different responses to amphetamine, a typical psychostimulant. Amphetamine 172-183 adenylate cyclase activating polypeptide 1 Mus musculus 17-22 19270432-2 2009 Our previous study also showed that hyperactivity in mice lacking pituitary adenylate cyclase-activating polypeptide (PACAP) was ameliorated by amphetamine in a serotonin (5-HT)(1A)-dependent manner and that amphetamine calmed wild-type mice given the 5-HT(1A) agonist 8-OH-DPAT. Amphetamine 144-155 adenylate cyclase activating polypeptide 1 Mus musculus 66-124 16687500-3 2006 In this study, Adcyap1(-/-) mice showed sensory-motor gating deficits, measured as deficits in prepulse inhibition (PPI), and showed normal PPI in response to amphetamine. Amphetamine 159-170 adenylate cyclase activating polypeptide 1 Mus musculus 15-22 16687500-4 2006 Amphetamine also significantly decreased hyperlocomotion in Adcyap1(-/-) mice, and this paradoxical antihyperkinetic effect depended on serotonin 1A (5-HT(1A)) receptor signaling. Amphetamine 0-11 adenylate cyclase activating polypeptide 1 Mus musculus 60-67 16687500-5 2006 c-Fos-positive neurons were increased in the prefrontal cortex in amphetamine-treated Adcyap1(-/-) mice, suggesting increased inhibitory control by prefrontal neurons. Amphetamine 66-77 adenylate cyclase activating polypeptide 1 Mus musculus 86-93