PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31905343-6 2020 The combined treatment of aspirin and cisplatin suppressed the expression of the anti-apoptotic protein Bcl-2 and the EMT-related proteins, up-regulated the levels of the cleaved PARP and Bax, and blocked the PI3K/AKT and RAF-MEK-ERK signaling pathway. Aspirin 26-33 zinc fingers and homeoboxes 2 Homo sapiens 222-225 23800934-2 2013 Experimental evidence implicates a role of RAF kinases in up-regulation of prostaglandin-endoperoxide synthase 2 (PTGS2, cyclooxygenase 2), suggesting that BRAF-mutant colonic cells might be less sensitive to the antitumor effects of aspirin than BRAF-wild-type neoplastic cells. Aspirin 234-241 zinc fingers and homeoboxes 2 Homo sapiens 43-46