PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8187462-11	1994	Aspirin, 325 mg/d, should be administered to patients with ECAD.	Aspirin	0-7	cadherin 1	Homo sapiens	59-63	
11401513-0	2001	Aspirin inhibits matrix metalloproteinase-2 activity, increases E-cadherin production, and inhibits in vitro invasion of tumor cells.	Aspirin	0-7	cadherin 1	Homo sapiens	64-74	
11401513-8	2001	Aspirin treatment also increased the production of the cell adhesion molecule, E-cadherin, in Hep G2 cancer cells.	Aspirin	0-7	cadherin 1	Homo sapiens	79-89	
11401513-11	2001	These results indicate that aspirin can modulate both MMP-2 and E-cadherin production and therein may possess antimetastatic effect.	Aspirin	28-35	cadherin 1	Homo sapiens	64-74	
30013667-4	2018	Furthermore, aspirin plus erlotinib significantly induced the activation of E-cadherin and suppression of p38.	Aspirin	13-20	cadherin 1	Homo sapiens	76-86	
30013667-6	2018	As p38 and E-cadherin also serve a key role in epithelial-to-mesenchymal transition (EMT) and cancer metastasis, we hypothesized that the combination of aspirin and erlotinib may significantly inhibit tumor metastasis.	Aspirin	153-160	cadherin 1	Homo sapiens	11-21	
30013667-5	2018	The data also indicated that the p38/E-cadherin pathway may be involved in the apoptosis caused by the combination of aspirin and erlotinib.	Aspirin	118-125	cadherin 1	Homo sapiens	37-47	
29042646-4	2017	Aspirin use was associated with a significant reduction of CDH1 methylation in AM (OR: 0.15, 95% CI: 0.06-0.41, p = 0.0002), but was less effective in reversing the methylation that occurred in IM.	Aspirin	0-7	cadherin 1	Homo sapiens	59-63	
19184424-0	2010	Chronic aspirin use suppresses CDH1 methylation in human gastric mucosa.	Aspirin	8-15	cadherin 1	Homo sapiens	31-35	
26810856-0	2016	Aspirin inhibits epithelial-to-mesenchymal transition and migration of oncogenic K-ras-expressing non-small cell lung carcinoma cells by down-regulating E-cadherin repressor Slug.	Aspirin	0-7	cadherin 1	Homo sapiens	153-163	
26810856-8	2016	Aspirin inhibits EMT and decelerates the migratory potential of A549 cells by down-regulating Slug and thereby up-regulating E-cadherin.	Aspirin	0-7	cadherin 1	Homo sapiens	125-135	
19184424-4	2010	We investigated the methylation status of CDH1 in noncancerous gastric mucosa in chronic aspirin user, and assessed its effect on methylation-associated carcinogenesis.	Aspirin	89-96	cadherin 1	Homo sapiens	42-46	
19184424-8	2010	CDH1 methylation more frequently occurred in H. pylori-infection-positive subjects (P < 0.0001), while chronic aspirin users had a significantly lower risk of CDH1 methylation [nonuser versus user 36.1% versus 10.8%; odds ratio (OR) = 0.21, 95% confidence interval (CI) = 0.07-0.63, P = 0.005].	Aspirin	114-121	cadherin 1	Homo sapiens	162-166	
19184424-9	2010	Logistic regression analysis showed that chronic aspirin use was the independent factor for lower risk of CDH1 methylation (adjusted OR = 0.21, 95%CI = 0.07-0.66, P = 0.008).	Aspirin	49-56	cadherin 1	Homo sapiens	106-110	
19184424-10	2010	Chronic aspirin use was associated with lower risk of CDH1 methylation in H. pylori-positive subjects (nonuser versus user 49.5% versus 19.0%; OR = 0.24, 95%CI = 0.08-0.76, P = 0.01).	Aspirin	8-15	cadherin 1	Homo sapiens	54-58	
19184424-13	2010	Our data suggest that chronic aspirin use is associated with reduced risk of CDH1 methylation in human gastric mucosa.	Aspirin	30-37	cadherin 1	Homo sapiens	77-81