PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2324733-0 1990 Influence of aspirin and iron(III) tetrasulfonated phthalocyanine on bilirubin binding by human serum albumin. Aspirin 13-20 albumin Homo sapiens 96-109 2011121-0 1991 Acetylsalicylate-human serum albumin interaction as studied by NMR spectroscopy--antigenicity-producing mechanism of acetylsalicylic acid. Aspirin 0-16 albumin Homo sapiens 23-36 2011121-0 1991 Acetylsalicylate-human serum albumin interaction as studied by NMR spectroscopy--antigenicity-producing mechanism of acetylsalicylic acid. Aspirin 117-137 albumin Homo sapiens 23-36 2011121-1 1991 To discover the antigenicity-producing mechanism of acetylsalicylic acid, the interaction of this drug and relevant salicylic acid with human serum albumin (HSA) has been studied by means of nuclear magnetic resonance (NMR) spectroscopy. Aspirin 52-72 albumin Homo sapiens 142-155 2324733-1 1990 The interaction of bilirubin with aspirin-modified human serum albumin (HSA) and the influence of iron tetrasulfonated phthalocyanine on bilirubin binding by the native protein has been studied by difference spectroscopy and circular dichroism measurements. Aspirin 34-41 albumin Homo sapiens 57-70 2621419-7 1989 Moreover, 12-HETE production in the presence of albumin was markedly increased and prolonged after aspirin treatment. Aspirin 99-106 albumin Homo sapiens 48-55 34693854-5 2022 Subsequent multivariate regression analysis showed heart rate (p <.001, OR = 0.978, 95%CI 0.969-0.987) and albumin (p =.019, OR = 0.658, 95%CI 0.464-0.933) were independent factors for aspirin-therapy after bleeding. Aspirin 185-192 albumin Homo sapiens 107-114 34239442-1 2021 Objective: To investigate the impact of albumin levels on the aspirin efficacy, since aspirin inhibits platelet aggregation (PA) by cyclooxygenase one irreversible acetylation that is less effective in patients with type 2 diabetes mellitus (T2DM). Aspirin 62-69 albumin Homo sapiens 40-47 34239442-9 2021 Conclusion: In T2DM patients, the efficacy of aspirin varies according to albumin levels. Aspirin 46-53 albumin Homo sapiens 74-81 34202801-2 2021 In this research, the selected drugs commonly used in diabetes and its comorbidities (gliclazide, cilazapril, atorvastatin, and acetylsalicylic acid) were studied for their interactions with bovine serum albumin-native and glycated. Aspirin 128-148 albumin Homo sapiens 198-211 6864486-7 1983 Acetylation of the lysine-199 residue with aspirin and 5-nitroaspirin decreased the trinitrophenylation rate of albumin with I. Aspirin 43-50 albumin Homo sapiens 112-119 3888490-9 1985 Both aspirin and salicylic acid are bound to serum albumin (aspirin being capable of irreversibly acetylating many proteins), and both are distributed in the synovial cavity, central nervous system, and saliva. Aspirin 5-12 albumin Homo sapiens 45-58 3888490-9 1985 Both aspirin and salicylic acid are bound to serum albumin (aspirin being capable of irreversibly acetylating many proteins), and both are distributed in the synovial cavity, central nervous system, and saliva. Aspirin 60-67 albumin Homo sapiens 45-58 32325408-0 2020 Interaction between aspirin and vitamin C with human serum albumin as binary and ternary systems. Aspirin 20-27 albumin Homo sapiens 59-66 4105907-1 1971 V. The interaction of phenylbutazone, flufenamic acid, and dicoumarol with acetylsalicylic acid-treated human serum albumin. Aspirin 75-95 albumin Homo sapiens 110-123 5773090-0 1969 Structural changes in human serum albumin induced by ingestion of acetylsalicylic acid. Aspirin 66-86 albumin Homo sapiens 34-41 5773090-1 1969 Acetylsalicylic acid (aspirin) acetylates human serum albumin under physiologic conditions in vitro. Aspirin 0-20 albumin Homo sapiens 54-61 5773090-1 1969 Acetylsalicylic acid (aspirin) acetylates human serum albumin under physiologic conditions in vitro. Aspirin 22-29 albumin Homo sapiens 54-61 5773090-3 1969 Albumin was reacted in vitro with aspirin labeled with (14)carbon at the acetyl-1 or the carboxyl carbon. Aspirin 34-41 albumin Homo sapiens 0-7 5773090-10 1969 A transacetylation reaction between aspirin and human albumin occurs in vivo and is similar to that observed in vitro. Aspirin 36-43 albumin Homo sapiens 54-61 7203849-2 1980 The effect of aspirin (ASP) on the binding of ascorbic acid (AA) to bovine serum albumin (BSA) has been investigated by the method of dynamic dialysis. Aspirin 14-21 albumin Homo sapiens 75-88 7203849-2 1980 The effect of aspirin (ASP) on the binding of ascorbic acid (AA) to bovine serum albumin (BSA) has been investigated by the method of dynamic dialysis. Aspirin 23-26 albumin Homo sapiens 75-88 5651209-0 1968 Acetylation of human serum albumin by acetylsalicylic acid. Aspirin 38-58 albumin Homo sapiens 27-34 5651209-1 1968 Human serum albumin is acetylated when exposed to acetylsalicylic acid (aspirin) under physiologic conditions in vitro. Aspirin 50-70 albumin Homo sapiens 12-19 5651209-1 1968 Human serum albumin is acetylated when exposed to acetylsalicylic acid (aspirin) under physiologic conditions in vitro. Aspirin 72-79 albumin Homo sapiens 12-19 16419075-0 2006 Competition of cytarabine and aspirin in binding to serum albumin in multidrug therapy. Aspirin 30-37 albumin Homo sapiens 52-65 32544082-2 2020 We aimed to elucidate the combined impact of BMI and dysglycemia expressed by glycated albumin (GA) on efficacy of clopidogrel-aspirin therapy among minor stroke (MS) or transient ischemic attack (TIA) patients. Aspirin 127-134 albumin Homo sapiens 87-94 31791286-7 2019 RESULTS: It was helpful for clinicians to make a decision for personalized prophylactic aspirin or warfarin in primary MN patients when serum albumin was < 3.2 g/dl to prevent arterial and venous thromboembolic events (VTEs). Aspirin 88-95 albumin Homo sapiens 142-149 27989119-4 2017 Alb forms adducts with many therapeutic drugs or their reactive metabolites such as beta-lactam antibiotics, acetylsalicylic acid, acetaminophen, nonsteroidal anti-inflammatory drugs, chemotherapeutic agents, and antiretroviral therapy drugs. Aspirin 109-129 albumin Homo sapiens 0-3 21995892-0 2011 Interaction of aspirin and vitamin C with bovine serum albumin. Aspirin 15-22 albumin Homo sapiens 49-62 21995892-4 2011 In this report, the competitive binding of vitamin C and aspirin to bovine serum albumin has been studied using constant protein concentration and various drug concentrations at pH 7.2. Aspirin 57-64 albumin Homo sapiens 75-88 21856214-6 2011 PBZ and ASA change the affinity of each other to the binding site in serum albumin (SA). Aspirin 8-11 albumin Homo sapiens 69-82 21856214-10 2011 The decrease of K(aII) values suggests that the competition between PBZ and ASA in binding to serum albumin in the second class of binding sites occurs. Aspirin 76-79 albumin Homo sapiens 94-107 21696233-1 2011 The interaction between cyclophosphamide hydrochloride (CYC) and aspirin (ASA) with human serum albumin (HSA) was studied by various kind of spectroscopic, zeta potential and molecular modeling under physiological conditions. Aspirin 74-77 albumin Homo sapiens 90-103 26328807-10 2016 It is also, observed that the gradual addition of HSA has led to a marked increase in fluorescence anisotropy (r) of Amlodipine and Aspirin which can be suggested that the drugs were located in a restricted environment of the protein as confirmed by Red Edge Excitation Shift (REES) studies. Aspirin 132-139 albumin Homo sapiens 50-53 26328807-12 2016 CONCLUSIONS: The present experiment showed that the binding of Amlodipine and Aspirin to HSA induced a conformational change of HSA. Aspirin 78-85 albumin Homo sapiens 89-92 26328807-12 2016 CONCLUSIONS: The present experiment showed that the binding of Amlodipine and Aspirin to HSA induced a conformational change of HSA. Aspirin 78-85 albumin Homo sapiens 128-131 25031079-6 2014 We report that curcumin has shown comparable binding affinity value vis-a-vis standard, the accessible surface area (ASA) of human serum albumin (uncomplexed) and its docked complex with curcumin at both binding sites was calculated and found to be close to that of warfarin and diazepam respectively. Aspirin 117-120 albumin Homo sapiens 131-144 23251150-0 2012 A molecular dynamics approach to ligand-receptor interaction in the aspirin-human serum albumin complex. Aspirin 68-75 albumin Homo sapiens 82-95 23251150-1 2012 In this work, we present a study of the interaction between human serum albumin (HSA) and acetylsalicylic acid (ASA, C(9)H(8)O(4)) by molecular dynamics simulations (MD). Aspirin 90-110 albumin Homo sapiens 66-79 23251150-1 2012 In this work, we present a study of the interaction between human serum albumin (HSA) and acetylsalicylic acid (ASA, C(9)H(8)O(4)) by molecular dynamics simulations (MD). Aspirin 112-115 albumin Homo sapiens 66-79 21856214-0 2011 A spectroscopic study of phenylbutazone and aspirin bound to serum albumin in rheumatoid diseases. Aspirin 44-51 albumin Homo sapiens 61-74 21856214-4 2011 Using fluorescence spectroscopy the location of binding site in serum albumin (SA) for PBZ and ASA was found. Aspirin 95-98 albumin Homo sapiens 64-77 21696233-0 2011 Investigations with spectroscopy, zeta potential and molecular modeling of the non-cooperative behaviour between cyclophosphamide hydrochloride and aspirin upon interaction with human serum albumin: binary and ternary systems from multi-drug therapy. Aspirin 148-155 albumin Homo sapiens 184-197 21696233-1 2011 The interaction between cyclophosphamide hydrochloride (CYC) and aspirin (ASA) with human serum albumin (HSA) was studied by various kind of spectroscopic, zeta potential and molecular modeling under physiological conditions. Aspirin 65-72 albumin Homo sapiens 90-103 18280093-11 2008 Multivariate analysis showed being ASA IIIA or IIIB is an independent predictor of survival, after adjusting for age, coronary artery disease, hyperlipidemia, COPD, and preoperative albumin levels. Aspirin 35-38 albumin Homo sapiens 182-189 16419075-1 2006 The aim of this study was to describe a competition between cytarabine (araC) and aspirin (ASA) in binding with bovine serum albumin (BSA). Aspirin 82-89 albumin Homo sapiens 119-132 16419075-1 2006 The aim of this study was to describe a competition between cytarabine (araC) and aspirin (ASA) in binding with bovine serum albumin (BSA). Aspirin 91-94 albumin Homo sapiens 119-132 15806298-0 2005 Aspirin blocks binding of photosensitizer SnET2 into human serum albumin: implications for photodynamic therapy. Aspirin 0-7 albumin Homo sapiens 59-72