PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20824505-0	2011	Renin-angiotensin system associated with risk of upper GI mucosal injury induced by low dose aspirin: renin angiotensin system genes" polymorphism.	Aspirin	93-100	renin	Homo sapiens	0-5	
20824505-0	2011	Renin-angiotensin system associated with risk of upper GI mucosal injury induced by low dose aspirin: renin angiotensin system genes" polymorphism.	Aspirin	93-100	renin	Homo sapiens	102-107	
12468886-15	2002	It seems likely that drugs currently used in the treatment of stroke, such as aspirin, statins, and modulators of the renin-angiotensin-aldosterone system, act at least partly via antiinflammatory mechanisms.	Aspirin	78-85	renin	Homo sapiens	118-123	
19805643-0	2009	Time-dependent effects of low-dose aspirin on plasma renin activity, aldosterone, cortisol, and catecholamines.	Aspirin	35-42	renin	Homo sapiens	53-58	
19805643-3	2009	We investigated the effect of 100 mg of aspirin administered at bedtime compared with administration on awakening on plasma renin activity and aldosterone levels over 24 hours and excretion of cortisol and catecholamines in 24-hour urine samples.	Aspirin	40-47	renin	Homo sapiens	124-129	
19805643-7	2009	Aspirin intake at bedtime compared with on awakening reduced average (24-hour) plasma renin activity by 0.08 microg/L per hour (95% CI: 0.03 to 0.13 microg/L per hour; P=0.003) without affecting aldosterone levels (95% CI: -0.01 to 0.01 nmol/L; P=0.93).	Aspirin	0-7	renin	Homo sapiens	86-91	
19805643-9	2009	In conclusion, aspirin taken at bedtime compared with on awakening significantly diminished 24-hour plasma renin activity and excretion of cortisol, dopamine, and norepinephrine in 24-hour urine.	Aspirin	15-22	renin	Homo sapiens	107-112	
14871051-9	2004	Although not discussed in detail, it is acknowledged that both hygienic measures (weight loss and aerobic exercise) and treatment strategies that include aspirin, statins, INS sensitizers, and antihypertensive agents that reduce renin-angiotensin-aldosterone system activity have been shown to reduce inflammation, coagulation abnormalities, endothelial function, proteinuria, and in some cases reduce CVD and renal disease progression.	Aspirin	154-161	renin	Homo sapiens	229-234	
18794027-2	2008	AIM: To study renal effects of different doses of aspirin in elderly healthy volunteers who had an activated renin-angiotensin system.	Aspirin	50-57	renin	Homo sapiens	109-114	
18256393-1	2008	BACKGROUND: Intensified multifactorial intervention - with tight glucose regulation and the use of renin-angiotensin system blockers, aspirin, and lipid-lowering agents - has been shown to reduce the risk of nonfatal cardiovascular disease among patients with type 2 diabetes mellitus and microalbuminuria.	Aspirin	134-141	renin	Homo sapiens	99-104	
11246058-7	2001	A possible interaction between ACE-I and aspirin might theoretically lead to reduced levels of renin activity in patients on aspirin, but we did not find any such inter-group difference.	Aspirin	41-48	renin	Homo sapiens	95-100	
11246058-7	2001	A possible interaction between ACE-I and aspirin might theoretically lead to reduced levels of renin activity in patients on aspirin, but we did not find any such inter-group difference.	Aspirin	125-132	renin	Homo sapiens	95-100	
624453-7	1978	In addition, use of anti-inflammatory drugs such as aspirin significantly lowers renin levels.	Aspirin	52-59	renin	Homo sapiens	81-86	
9289376-11	1997	In them, and not in the remaining patients in each group, aspirin substantially attenuated the renin rise elicited by ACE-inhibition.	Aspirin	58-65	renin	Homo sapiens	95-100	
9289376-12	1997	These data suggest that: a dosage of 100 mg aspirin is devoid of any inhibitory effect; more that 50% of ACE inhibited patients are, at least in the short term, susceptible to the action of 300 mg aspirin, regardless of the severity of hypertension; counteraction is seemingly mediated through a prostaglandin inhibition and depends on the individual predominance of prostaglandin activation (also as a renin secretory stimulus) or angiotensin inhibition by the ACE-inhibitor.	Aspirin	197-204	renin	Homo sapiens	403-408	
8829212-6	1996	Renin caused a more rapid recovery of decidual prostaglandin biosynthesis from acetylsalicylic acid treatment than did control media.	Aspirin	79-99	renin	Homo sapiens	0-5	
8665965-11	1995	These results suggest that the renin-angiotensin II system in the post-acute phase of AMI patients treated with aspirin and beta-blocking agents is correlated with cardiovascular autoregulation during postural manoeuvres.	Aspirin	112-119	renin	Homo sapiens	31-36	
3110670-3	1986	Administration of acetylsalicylic acid caused significant antidiuresis (-56%), antinatriuresis (-82%), renin suppression (-26%) and decreased GFR (-41%).	Aspirin	18-38	renin	Homo sapiens	103-108	
7872329-4	1995	Similarities with sclerodermatous kidney and an increase in plasma renin activity led us to initiate treatment with aspirin and captopril, with excellent control of the renal syndrome.	Aspirin	116-123	renin	Homo sapiens	67-72	
1838974-6	1991	In the six patients without azotemia, aspirin inhibited renal prostaglandin E2 synthesis and suppressed renin release from the ischemic kidney, resulting in lowered blood pressure.	Aspirin	38-45	renin	Homo sapiens	104-109	
1838974-8	1991	The reduction in blood pressure by angioplasty was correlated with the responses of blood pressure and renin release to aspirin.	Aspirin	120-127	renin	Homo sapiens	103-108	
33194862-11	2020	LEARNING POINTS: Polycythemia can cause erythromelalgia, which should be treated with aspirin.Primary aldosteronism causes secondary erythropoiesis through activation of the renin-aldosterone system, but the mechanism is not clear.Erythropoiesis may be promoted by concurrent primary aldosteronism and polycythemia vera, resulting in secondary erythromelalgia.	Aspirin	86-93	renin	Homo sapiens	174-179	
837964-3	1977	The effect of ASA on urinary sodium excretion was most prominent during day time (8 a.m.-10 p.m.) and on days with low sodium intake, as confirmed by control sodium excretion and plasma renin activity.	Aspirin	14-17	renin	Homo sapiens	186-191	
347802-0	1977	[The effect of diclofenac (voltaren) and acetylsalicylic acid (aspirin) on plasma renin activity in man].	Aspirin	41-61	renin	Homo sapiens	82-87	
347802-0	1977	[The effect of diclofenac (voltaren) and acetylsalicylic acid (aspirin) on plasma renin activity in man].	Aspirin	63-70	renin	Homo sapiens	82-87