PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24919794-0	2014	Quinazoline analog HMJ-30 inhibits angiogenesis: involvement of endothelial cell apoptosis through ROS-JNK-mediated death receptor 5 signaling.	6-fluoro-2-(3-fluorophenyl)-4-(cyanoanilino)quinazoline	19-25	mitogen-activated protein kinase 8	Homo sapiens	103-106	
24919794-8	2014	We investigated the upstream of the death receptor pathway and further observed that the levels of death receptor 5 (DR5) and phosphorylated c-Jun N-terminal kinase (JNK) signals were upregulated in HUVECs following HMJ-30 challenge, which was confirmed by a JNK-specific inhibitor (SP600125).	6-fluoro-2-(3-fluorophenyl)-4-(cyanoanilino)quinazoline	216-222	mitogen-activated protein kinase 8	Homo sapiens	141-164	
24919794-8	2014	We investigated the upstream of the death receptor pathway and further observed that the levels of death receptor 5 (DR5) and phosphorylated c-Jun N-terminal kinase (JNK) signals were upregulated in HUVECs following HMJ-30 challenge, which was confirmed by a JNK-specific inhibitor (SP600125).	6-fluoro-2-(3-fluorophenyl)-4-(cyanoanilino)quinazoline	216-222	mitogen-activated protein kinase 8	Homo sapiens	166-169	
24919794-8	2014	We investigated the upstream of the death receptor pathway and further observed that the levels of death receptor 5 (DR5) and phosphorylated c-Jun N-terminal kinase (JNK) signals were upregulated in HUVECs following HMJ-30 challenge, which was confirmed by a JNK-specific inhibitor (SP600125).	6-fluoro-2-(3-fluorophenyl)-4-(cyanoanilino)quinazoline	216-222	mitogen-activated protein kinase 8	Homo sapiens	259-262	
24919794-9	2014	Hence, HMJ-30-induced endothelial cell apoptosis involved the ROS/JNK-regulated DR5 pathway.	6-fluoro-2-(3-fluorophenyl)-4-(cyanoanilino)quinazoline	7-13	mitogen-activated protein kinase 8	Homo sapiens	66-69