PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22644860-1	2012	The concentrative nucleoside transporter CNT1 and equilibrated nucleoside transporter ENT1 mediate the cellular uptake of naturally occurring pyrimidine and purine nucleosides and many structurally diverse anticancer and antiviral nucleoside analogs, thereby regulating drug responses or toxicity at the target site.	purine	157-163	solute carrier family 29 member 1 (Augustine blood group)	Homo sapiens	86-90	
14978234-10	2004	Addition of a hydroxyl group around the 2-position of purine (or 3-position of pyrimidine) may increase inhibition to hCNT2 transporter; addition of hydroxyl group around the 2,7-position of purine (or the 3,5-position of pyrimidine) would increase the inhibition to hENT1 transporter.	purine	54-60	solute carrier family 29 member 1 (Augustine blood group)	Homo sapiens	267-272	
21795683-2	2011	Both transport purine and pyrimidine nucleosides and are distinguished functionally by a difference in sensitivity to inhibition by nanomolar concentrations of nitrobenzylmercaptopurine ribonucleoside (NBMPR), hENT1 being NBMPR-sensitive.	purine	15-21	solute carrier family 29 member 1 (Augustine blood group)	Homo sapiens	210-215	
20113503-13	2010	CONCLUSION: Collectively, the data obtained in this study clearly show that the endogenous host erythrocyte transporters hENT1 and hFNT1, rather than the NPP, are the major route of entry of purine into parasitized RBC.	purine	191-197	solute carrier family 29 member 1 (Augustine blood group)	Homo sapiens	121-126	
20113503-14	2010	Inhibitors of hENT1 and hFNT1, as well as the NPP, should be considered in the development of anti-malarials targeted to purine transport.	purine	121-127	solute carrier family 29 member 1 (Augustine blood group)	Homo sapiens	14-19	
18668437-6	2008	The best-characterized members of the family, hENT1 and hENT2, possess similar broad permeant selectivities for purine and pyrimidine nucleosides, but hENT2 also efficiently transports nucleobases.	purine	112-118	solute carrier family 29 member 1 (Augustine blood group)	Homo sapiens	46-51	
17346175-5	2007	In humans, purine uptake into many cell types is mediated by members of the Equilibrative Nucleoside Transporter (ENT) family, in particular hENT1 and hENT2.	purine	11-17	solute carrier family 29 member 1 (Augustine blood group)	Homo sapiens	141-146	
12440703-1	2002	The human equilibrative nucleoside transporters I and 2 (hENT1, hENT2) share 50% amino acid identity and exhibit broad selectivities, accepting purine and pyrimidine nucleosides as permeants.	purine	144-150	solute carrier family 29 member 1 (Augustine blood group)	Homo sapiens	57-62	
12838422-4	2004	The best-characterised members of the family, hENT1 and hENT2, possess similar broad substrate specificities for purine and pyrimidine nucleosides, but hENT2 in addition efficiently transports nucleobases.	purine	113-119	solute carrier family 29 member 1 (Augustine blood group)	Homo sapiens	46-51	
27009875-8	2016	These findings suggest that ENT1 is regulated via receptor-dependent calcium-linked pathways resulting in an alteration of purine flux, which may modulate purinergic signaling and influence NA drug efficacy.	purine	123-129	solute carrier family 29 member 1 (Augustine blood group)	Homo sapiens	28-32	
9705281-3	1998	When expressed in Xenopus oocytes, recombinant hENT1 and rENT1 transport both purine and pyrimidine nucleosides, including adenosine, and are inhibited by nanomolar concentrations of NBMPR.	purine	78-84	solute carrier family 29 member 1 (Augustine blood group)	Homo sapiens	47-52