PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33972798-0	2021	Cell-surface SLC nucleoside transporters and purine levels modulate BRD4-dependent chromatin states.	purine	45-51	bromodomain containing 4	Homo sapiens	68-72	
33972798-6	2021	Intersection of the two orthogonal approaches reveal that loss of transporters involved with purine transport or inhibition of de novo purine synthesis lead to dysfunction of BRD4-dependent transcriptional regulation.	purine	93-99	bromodomain containing 4	Homo sapiens	175-179	
33972798-6	2021	Intersection of the two orthogonal approaches reveal that loss of transporters involved with purine transport or inhibition of de novo purine synthesis lead to dysfunction of BRD4-dependent transcriptional regulation.	purine	135-141	bromodomain containing 4	Homo sapiens	175-179	
33972798-7	2021	Through mechanistic characterization of the metabolic circuitry, we elucidate the convergence of SLC-mediated purine uptake and de novo purine synthesis on BRD4-chromatin occupancy.	purine	110-116	bromodomain containing 4	Homo sapiens	156-160	
33972798-7	2021	Through mechanistic characterization of the metabolic circuitry, we elucidate the convergence of SLC-mediated purine uptake and de novo purine synthesis on BRD4-chromatin occupancy.	purine	136-142	bromodomain containing 4	Homo sapiens	156-160	
33972798-8	2021	Moreover, adenine-related metabolite supplementation effectively restores BRD4 functionality on purine impairment.	purine	96-102	bromodomain containing 4	Homo sapiens	74-78	
33972798-9	2021	Our study highlights the specific role of purine/adenine metabolism in modulating BRD4-dependent epigenetic states.	purine	42-48	bromodomain containing 4	Homo sapiens	82-86