PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26256403-10	2015	SAR study on its derivatives showed that the alkyl substituent on the alpha-position of the left-side benzylic amine (R1) was essential for Ca(2+) influx inhibition and that the S-configuration was better than the R-configuration.	Amines	111-116	sarcosine dehydrogenase	Homo sapiens	0-3	
30709651-2	2019	The results demonstrated that tertiary amine derivatives exhibited better cytotoxic activity, and SAR study revealed that electron-donating substituents on the phenyl ring of the derivatization functionality contributed to potent anticancer activities.	Amines	39-44	sarcosine dehydrogenase	Homo sapiens	98-101	
30015176-5	2018	The SAR study revealed that the substitution of phenyl ring with electron withdrawing group at R1 position and less bulky amines group at R2 position of 1,3,4-oxadiazole-2-thione ring showed significant growth inhibitory activity.	Amines	122-128	sarcosine dehydrogenase	Homo sapiens	4-7	
19524331-1	2009	A series of (4-aminobutyn-1-yl)benzylamines were prepared and the SAR around three key areas: (1) the amine attached to the butynyl linker (R(3)R(4)N-); (2) the benzylamine moiety (R(1)R(2)N-); and (3) the point of attachment of the benzylamine group (R(1)R(2)N- in the ortho, meta, or para positions) was examined.	Amines	37-42	sarcosine dehydrogenase	Homo sapiens	66-69	
20839775-3	2010	In this manuscript, we are reporting a detailed exploration of the region of the receptor interacting with the amine terminus of the scaffold wherein SAR and developability data associated with these novel templates was undertaken.	Amines	111-116	sarcosine dehydrogenase	Homo sapiens	150-153	
20045315-3	2010	SAR studies at the lactam nitrogen of the pharmacophore have suggested that a secondary or tertiary amine is important for cellular potency.	Amines	100-105	sarcosine dehydrogenase	Homo sapiens	0-3	
18334295-1	2008	Part 2: SAR of the amine tether.	Amines	19-24	sarcosine dehydrogenase	Homo sapiens	8-11	
15755642-0	2005	Pyrazolopyridine antiherpetics: SAR of C2" and C7 amine substituents.	Amines	50-55	sarcosine dehydrogenase	Homo sapiens	32-35	
14741270-3	2004	The SAR of the basic amine moiety was compared in three different series of analogues.	Amines	21-26	sarcosine dehydrogenase	Homo sapiens	4-7