PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27441242-0 2016 N-alkylated isatins evade P-gp mediated efflux and retain potency in MDR cancer cell lines. Isatin 12-19 ATP binding cassette subfamily B member 1 Homo sapiens 26-30 27441242-6 2016 We show that one mechanism by which the isatin-based compounds overcome MDR is by circumventing P-glycoprotein (P-gp) mediated drug efflux. Isatin 40-46 ATP binding cassette subfamily B member 1 Homo sapiens 96-110 27441242-6 2016 We show that one mechanism by which the isatin-based compounds overcome MDR is by circumventing P-glycoprotein (P-gp) mediated drug efflux. Isatin 40-46 ATP binding cassette subfamily B member 1 Homo sapiens 112-116 19397322-5 2009 The MDR1-selective pharmacophore highlights the importance of aromatic/hydrophobic features at the N4 position of the thiosemicarbazone and the reliance on the isatin moiety as key bioisosteric contributors. Isatin 160-166 ATP binding cassette subfamily B member 1 Homo sapiens 4-8