PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26288684-0 2015 Discovery of Novel Isatin-Based p53 Inducers. Isatin 19-25 tumor protein p53 Homo sapiens 32-35 33367935-3 2021 Mechanistically, isatin inhibited lysine-specific histone demethylase (LSD)1 and reversed the blockade on p53, thereby activating the apoptotic pathway. Isatin 17-23 tumor protein p53 Homo sapiens 106-109 31998813-0 2019 Novel Isatin-based activator of p53 transcriptional functions in tumor cells. Isatin 6-12 tumor protein p53 Homo sapiens 32-35 31998813-4 2019 Here, we report novel data on p53 activating Isatin-based Cu(II) complex exhibiting cytotoxic properties towards HCT116 and MCF7 tumor cell lines, as confirmed by cell viability assay and flow cytometry analysis of apoptosis. Isatin 45-51 tumor protein p53 Homo sapiens 30-33 30109812-0 2018 Novel isatin-derived molecules activate p53 via interference with Mdm2 to promote apoptosis. Isatin 6-12 tumor protein p53 Homo sapiens 40-43