PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18334118-9	2008	In addition, the proportion of SH-SY5Y cells at G1 phase was significantly increased with an apparent G1 phase arrest when treated with ISA (100, 200, 400 micromol/L) for 48 h. In the progress of cell cycle arrest induced by ISA, phosphorylated ERK and CDK1 expression were down-regulated (P<0.05).	Isatin	136-139	mitogen-activated protein kinase 1	Homo sapiens	245-248	
18334118-9	2008	In addition, the proportion of SH-SY5Y cells at G1 phase was significantly increased with an apparent G1 phase arrest when treated with ISA (100, 200, 400 micromol/L) for 48 h. In the progress of cell cycle arrest induced by ISA, phosphorylated ERK and CDK1 expression were down-regulated (P<0.05).	Isatin	225-228	mitogen-activated protein kinase 1	Homo sapiens	245-248	
33367935-4	2021	The inhibitory effect of isatin on LSD1 may be mediated via direct binding and molecular docking or indirectly through the TGFbeta/ERK/NF-kappaB signaling pathway.	Isatin	25-31	mitogen-activated protein kinase 1	Homo sapiens	131-134