PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35398259-7 2022 AKR1C1 and AKR1C4 also showed broad substrate specificity for nonsteroidal carbonyl compounds including endogenous 4-oxo-2-nonenal, 4-hydroxy-nonenal, acrolein, isocaproaldehyde, farnesal, isatin and methylglyoxal, of which 4-oxo-2-nonenal was reduced with the lowest Km value of 0.9microM. Isatin 189-195 aldo-keto reductase family 1 member C4 Homo sapiens 11-17