PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21615156-2	2011	One very promising PET tracer is (S)-1-(4-(2-[(18)F]-fluoroethoxy)benzyl)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatin (isatin), a caspase-3 inhibitor, which has been developed at the University Hospital of Munster to image cell death (apoptosis).	Isatin	117-123	caspase 3	Rattus norvegicus	136-145	
35453384-8	2022	Moreover, isatin significantly reduced the DENA/2-AAF-induced decrease in hepatic expression of anti-apoptotic Bcl2 and the DENA/2-AAF-induced increases in pro-inflammatory and pro-apoptotic factors (TNF-alpha, NF-kappaB p50, NF-kappaB p65, p53, and caspase 3).	Isatin	10-16	caspase 3	Rattus norvegicus	250-259	
16891117-0	2006	Synthesis, radiolabeling, and in vivo evaluation of an 18F-labeled isatin analog for imaging caspase-3 activation in apoptosis.	Isatin	67-73	caspase 3	Rattus norvegicus	93-102	
19647171-2	2009	Radiolabeled isatins bind to caspase-3 with high affinity and are potential tracers for use with positron emission tomography to image apoptosis.	Isatin	13-20	caspase 3	Rattus norvegicus	29-38	
19647171-3	2009	We compared the ability of two novel radiolabeled isatins, [18F]WC-IV-3 and [11C]WC-98, to detect caspase-3 activation in a rat model of cycloheximide-induced liver injury.	Isatin	50-57	caspase 3	Rattus norvegicus	98-107