PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17191919-3 2005 In this work, a new disubstituted indigoid generation system was developed with a tryptophanase-deficient Escherichia coli strain as a host to express the human cytochrome P450 2A6 mutant L240C/N297Q, which catalyzes the oxidation of indole to isatin and indoxyl, which in turn react to generate indigoids. Isatin 244-250 cytochrome P450 family 2 subfamily A member 6 Homo sapiens 161-180