PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17699663-4 2007 Two weeks after a methamphetamine binge (4 x 10 mg/kg, i.p., at 2 h intervals), GDNF(+/-) mice had a significantly greater reduction of tyrosine hydroxylase immunoreactivity in the medial striatum, a proportionally greater depletion of dopamine and 3,4-dihydroxyphenylacetic acid (DOPAC) levels in the striatum, and a greater increase in activated microglia in the substantia nigra than wild-type mice. 3,4-Dihydroxyphenylacetic Acid 253-279 glial cell line derived neurotrophic factor Mus musculus 80-84 17699663-4 2007 Two weeks after a methamphetamine binge (4 x 10 mg/kg, i.p., at 2 h intervals), GDNF(+/-) mice had a significantly greater reduction of tyrosine hydroxylase immunoreactivity in the medial striatum, a proportionally greater depletion of dopamine and 3,4-dihydroxyphenylacetic acid (DOPAC) levels in the striatum, and a greater increase in activated microglia in the substantia nigra than wild-type mice. 3,4-Dihydroxyphenylacetic Acid 281-286 glial cell line derived neurotrophic factor Mus musculus 80-84 17699663-5 2007 At 12 months of age, methamphetamine-treated GDNF(+/-) mice exhibited less motor activity and lower levels of tyrosine hydroxylase-immunoreactivity, dopamine, DOPAC, and serotonin than wild-type mice. 3,4-Dihydroxyphenylacetic Acid 159-164 glial cell line derived neurotrophic factor Mus musculus 45-49 16437537-5 2006 Also, the response of extracellular accumbal DOPAC to acute morphine was significantly altered in the GDNF+/- mice. 3,4-Dihydroxyphenylacetic Acid 45-50 glial cell line derived neurotrophic factor Mus musculus 102-106 15978005-3 2005 GDNF treatment (100 ng/mL) increased dopaminergic neuron soma size (up to 43%) and DOPAC production (approximately three-fold), but not the number of dopamine neurons in control cultures. 3,4-Dihydroxyphenylacetic Acid 83-88 glial cell line derived neurotrophic factor Mus musculus 0-4