PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32792862-0 2020 Jagged2 progressively increased expression from Stage I to III of Bladder Cancer and Melatonin-mediated downregulation of Notch/Jagged2 suppresses the Bladder Tumorigenesis via inhibiting PI3K/AKT/mTOR/MMPs signaling. Melatonin 85-94 jagged canonical Notch ligand 2 Homo sapiens 0-7 32792862-0 2020 Jagged2 progressively increased expression from Stage I to III of Bladder Cancer and Melatonin-mediated downregulation of Notch/Jagged2 suppresses the Bladder Tumorigenesis via inhibiting PI3K/AKT/mTOR/MMPs signaling. Melatonin 85-94 jagged canonical Notch ligand 2 Homo sapiens 128-135 32792862-1 2020 Background: This study assessed the expression of Jagged2 in human bladder cancer (BC) tested the hypothesis that melatonin (Mel) inhibited the tumorigenesis of BC cells mainly through downregulating the Notch/Jagged2 and PI3K/AKT/mTOR/MMPs(2&9) signaling pathways. Melatonin 114-123 jagged canonical Notch ligand 2 Homo sapiens 50-57 32792862-1 2020 Background: This study assessed the expression of Jagged2 in human bladder cancer (BC) tested the hypothesis that melatonin (Mel) inhibited the tumorigenesis of BC cells mainly through downregulating the Notch/Jagged2 and PI3K/AKT/mTOR/MMPs(2&9) signaling pathways. Melatonin 114-123 jagged canonical Notch ligand 2 Homo sapiens 210-217 32792862-1 2020 Background: This study assessed the expression of Jagged2 in human bladder cancer (BC) tested the hypothesis that melatonin (Mel) inhibited the tumorigenesis of BC cells mainly through downregulating the Notch/Jagged2 and PI3K/AKT/mTOR/MMPs(2&9) signaling pathways. Melatonin 125-128 jagged canonical Notch ligand 2 Homo sapiens 50-57 32792862-1 2020 Background: This study assessed the expression of Jagged2 in human bladder cancer (BC) tested the hypothesis that melatonin (Mel) inhibited the tumorigenesis of BC cells mainly through downregulating the Notch/Jagged2 and PI3K/AKT/mTOR/MMPs(2&9) signaling pathways. Melatonin 125-128 jagged canonical Notch ligand 2 Homo sapiens 210-217 32792862-3 2020 In vitro study showed that in BC cell line of UMUC3, the cellular and protein expressions of Jagged2 were significantly attenuated in Mel-treated UMUC3 and further attenuated in UMUC3 shRNA silenced Notch/JAG2 (UMUC3KD) than in UMUC3 only (all p<0.0001). Melatonin 134-137 jagged canonical Notch ligand 2 Homo sapiens 93-100 32792862-3 2020 In vitro study showed that in BC cell line of UMUC3, the cellular and protein expressions of Jagged2 were significantly attenuated in Mel-treated UMUC3 and further attenuated in UMUC3 shRNA silenced Notch/JAG2 (UMUC3KD) than in UMUC3 only (all p<0.0001). Melatonin 134-137 jagged canonical Notch ligand 2 Homo sapiens 205-209