PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28473204-3 2017 Cirrhotic tissues had a higher ratio of epoxyeicosatrienoic acids (EETs) to dihydroxyeicosatrienoic acids (DHETs) following increased CYP2C11 expression, which may be a protective response. epoxyeicosatrienoic acids 40-65 cytochrome P450, subfamily 2, polypeptide 11 Rattus norvegicus 134-141 15637425-1 2005 BACKGROUND: Cytochrome P450 (CYP) isoenzymes (CYP2C and CYP2J) are involved in the production of epoxyeicosatrienoic acids, which are postulated as endothelium-derived hyperpolarizing factors (EDHFs). epoxyeicosatrienoic acids 97-122 cytochrome P450, subfamily 2, polypeptide 11 Rattus norvegicus 46-51 25055826-4 2014 Cytochrome P450 epoxygenases (Cyp4x1 and Cyp2c11) are expressed in the brain and vasculature and metabolize arachidonic acid (AA) to form epoxyeicosatrienoic acids (EETs). epoxyeicosatrienoic acids 138-163 cytochrome P450, subfamily 2, polypeptide 11 Rattus norvegicus 41-48 20732876-4 2010 CYP2C/2J isoforms converting AA to epoxyeicosatrienoic acids (EETs) preferentially epoxidized the omega-3 double bond and thereby produced 17,18-epoxyeicosatetraenoic (17,18-EEQ) and 19,20-epoxydocosapentaenoic acid (19,20-EDP) from EPA and DHA. epoxyeicosatrienoic acids 35-60 cytochrome P450, subfamily 2, polypeptide 11 Rattus norvegicus 0-7 24969701-6 2014 CYP2C11 produced epoxyeicosatrienoic acids (EETs) as 61.3%, and CYP2C6 produced midchain HETEs and EETs as 48.3 and 29.4%, respectively, of the total metabolites formed. epoxyeicosatrienoic acids 17-42 cytochrome P450, subfamily 2, polypeptide 11 Rattus norvegicus 0-7 15190971-3 2004 Since CYP2C11 and CYP2J4 convert arachidonic acid to vasodilative epoxyeicosatrienoic acids, and CYP4A3 metabolizes arachidonic acid to both epoxyeicosatrienoic acids and vasoconstrictive 19,20-hydroxyeicosatetraenoic acid, the aim of this study was to examine the expression of these isoforms in sepsis and their association with hemodynamic changes. epoxyeicosatrienoic acids 66-91 cytochrome P450, subfamily 2, polypeptide 11 Rattus norvegicus 6-13 15190971-3 2004 Since CYP2C11 and CYP2J4 convert arachidonic acid to vasodilative epoxyeicosatrienoic acids, and CYP4A3 metabolizes arachidonic acid to both epoxyeicosatrienoic acids and vasoconstrictive 19,20-hydroxyeicosatetraenoic acid, the aim of this study was to examine the expression of these isoforms in sepsis and their association with hemodynamic changes. epoxyeicosatrienoic acids 141-166 cytochrome P450, subfamily 2, polypeptide 11 Rattus norvegicus 6-13 12865253-1 2003 Nitric oxide (NO) inhibits hemoproteins, including cytochrome (CYP) 2C, the gene responsible for the production of epoxyeicosatrienoic acids (EETs). epoxyeicosatrienoic acids 115-140 cytochrome P450, subfamily 2, polypeptide 11 Rattus norvegicus 0-70