PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23521681-9	2013	High MGMT levels attenuate the pharmacodynamic effects of triazenes.	Triazenes	58-67	O-6-methylguanine-DNA methyltransferase	Homo sapiens	5-9	
16412662-2	2006	Two DNA repair enzyme systems, i.e. the O6-guanine-alkyl-transferase (MGMT) and mismatch repair (MMR), play a predominant role in conditioning the cytotoxic effects of triazenes.	Triazenes	168-177	O-6-methylguanine-DNA methyltransferase	Homo sapiens	70-74	
17500047-3	2007	High levels of O(6)-methylguanine-DNA methyltransferase (MGMT) or a defective mismatch repair (MMR) system, are associated with cellular resistance to triazenes.	Triazenes	151-160	O-6-methylguanine-DNA methyltransferase	Homo sapiens	15-55	
17500047-3	2007	High levels of O(6)-methylguanine-DNA methyltransferase (MGMT) or a defective mismatch repair (MMR) system, are associated with cellular resistance to triazenes.	Triazenes	151-160	O-6-methylguanine-DNA methyltransferase	Homo sapiens	57-61	
16412662-3	2006	In particular, high levels of MGMT associated with target cells are responsible of resistance to triazenes.	Triazenes	97-106	O-6-methylguanine-DNA methyltransferase	Homo sapiens	30-34	
16412662-9	2006	This drug is used in combination with triazene compounds in order to augment their anti-tumour efficacy against neoplastic cells endowed with high MGMT activity.	Triazenes	38-46	O-6-methylguanine-DNA methyltransferase	Homo sapiens	147-151	
32772433-6	2021	Mechanistic studies of chimera 7b suggest a dual mechanism of action: methylation of the DNA repairing protein MGMT associated with the triazene structural portion and Topo II inhibition by intercalation of the acridine core.	Triazenes	136-144	O-6-methylguanine-DNA methyltransferase	Homo sapiens	111-115