PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21191761-3	2010	In addition, danazol reduced cellular tyrosinase activity in B16 cells but did not directly inhibit the murine tyrosinase activity in the cell-free system.	Danazol	13-20	tyrosinase	Mus musculus	38-48	
21191761-4	2010	Western blotting analysis confirmed that danazol downregulated the levels of tyrosinase protein in B16 cells, and reverse-transcription polymerase chain reaction (RT-PCR) analysis revealed that danazol did not downregulate the levels of tyrosinase mRNA in the cells.	Danazol	41-48	tyrosinase	Mus musculus	77-87	
21191761-5	2010	These results indicate that danazol inhibits melanogenesis in B16 cells via reducing the tyrosinase activity by post-transcriptional regulation.	Danazol	28-35	tyrosinase	Mus musculus	89-99