PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34971698-0 2021 Glyoxal induces senescence in human keratinocytes through oxidative stress and activation of the AKT/FOXO3a/p27KIP1 pathway. Glyoxal 0-7 AKT serine/threonine kinase 1 Homo sapiens 97-100 34971698-6 2021 Furthermore, glyoxal-induced senescence bears a unique molecular progression profile: an "early-stage" when AKT-FOXO3a-p27KIP1 pathway mediates cell-cycle arrest, and a "late-stage" senescence maintained by the p16INK4/pRb pathway. Glyoxal 13-20 AKT serine/threonine kinase 1 Homo sapiens 108-111