PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11950021-10	2002	ACECLO, DICLO, INDO, NIM significantly inhibited basal and IL-1beta stimulated IL-6 production; CELE and IBUP only inhibited IL-1beta stimulated IL-6 production; and ROFE and PIROX had no significant effects.	aceclofenac	0-6	interleukin 1 beta	Homo sapiens	59-67	
10807502-5	2000	RESULTS: 4"-Hydroxy aceclofenac, a major metabolite of aceclofenac, down-regulated both basal and IL-1beta-induced production of proMMP-1 and proMMP-3 at a concentration sufficient to suppress PGE2 production without modulating proMMP-2 or TIMP-1, whereas aceclofenac itself had no marked effect on the production of proMMPs.	aceclofenac	20-31	interleukin 1 beta	Homo sapiens	98-106	
11556519-8	2001	RESULTS: We have demonstrated that aceclofenac, 4"-hydroxyaceclofenac and diclofenac significantly decreased interleukin-6 production at concentrations ranged among 1 to 30 microM and fully blocked prostaglandin E2 synthesis by IL-1beta- or LPS-stimulated human chondrocytes.	aceclofenac	35-46	interleukin 1 beta	Homo sapiens	228-236	
10807502-5	2000	RESULTS: 4"-Hydroxy aceclofenac, a major metabolite of aceclofenac, down-regulated both basal and IL-1beta-induced production of proMMP-1 and proMMP-3 at a concentration sufficient to suppress PGE2 production without modulating proMMP-2 or TIMP-1, whereas aceclofenac itself had no marked effect on the production of proMMPs.	aceclofenac	55-66	interleukin 1 beta	Homo sapiens	98-106	
9226412-3	1997	Aceclofenac inhibited interleukin-1beta-induced prostaglandin E2 production by human rheumatoid synovial cells, but had no inhibitory effect on cyclooxygenase-1 or cyclooxygenase-2 activities by itself.	aceclofenac	0-11	interleukin 1 beta	Homo sapiens	22-39