PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12966366-9	2003	Moreover, ex vivo COX-1-dependent thromboxane B(2) synthesis was inhibited significantly less by aceclofenac than by diclofenac.	aceclofenac	97-108	mitochondrially encoded cytochrome c oxidase I	Homo sapiens	18-23	
12966366-11	2003	Although 100 mg aceclofenac yielded diclofenac concentrations substantially lower than 75 mg diclofenac, these were sufficient for a sustained block of COX-2 but caused a minor and shorter inhibition of COX-1 than 75 mg diclofenac.	aceclofenac	16-27	mitochondrially encoded cytochrome c oxidase I	Homo sapiens	203-208	
12966366-12	2003	In conclusion, both COX-1-sparing and COX-2-inhibitory actions of aceclofenac may rest in its limited but sustained biotransformation to diclofenac.	aceclofenac	66-77	mitochondrially encoded cytochrome c oxidase I	Homo sapiens	20-25	
11556519-13	2001	In the whole blood test, aceclofenac and 4"-hydroxyaceclofenac weakly inhibited COX-1 with IC50 values superior to 100 microM, but decreased by 50% COX-2 activity at the concentration of 0.77 and 36 microM, respectively.	aceclofenac	25-36	mitochondrially encoded cytochrome c oxidase I	Homo sapiens	80-85