PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15050431-0 2004 ALS-like skin changes in mice on a chronic low-Ca/Mg high-Al diet. Aluminum 58-60 superoxide dismutase 1 Homo sapiens 0-3 18172803-7 2008 A strong inverse relationship was found between serum Al (Al-S) and CC16 concentrations (p = 0.006). Aluminum 54-56 superoxide dismutase 1 Homo sapiens 58-62 16679054-0 2006 Study on the interaction of copper-zinc superoxide dismutase with aluminum ions by electrochemical and fluorescent method. Aluminum 66-74 superoxide dismutase 1 Homo sapiens 40-60 16679054-1 2006 The interaction of superoxide dismutase (SOD) with aluminum (Al) ions was investigated by cyclic voltammetry, fluorescence spectroscopy and synchronous fluorescence spectroscopy. Aluminum 51-59 superoxide dismutase 1 Homo sapiens 19-39 16679054-1 2006 The interaction of superoxide dismutase (SOD) with aluminum (Al) ions was investigated by cyclic voltammetry, fluorescence spectroscopy and synchronous fluorescence spectroscopy. Aluminum 51-59 superoxide dismutase 1 Homo sapiens 41-44 16679054-1 2006 The interaction of superoxide dismutase (SOD) with aluminum (Al) ions was investigated by cyclic voltammetry, fluorescence spectroscopy and synchronous fluorescence spectroscopy. Aluminum 61-63 superoxide dismutase 1 Homo sapiens 19-39 16679054-1 2006 The interaction of superoxide dismutase (SOD) with aluminum (Al) ions was investigated by cyclic voltammetry, fluorescence spectroscopy and synchronous fluorescence spectroscopy. Aluminum 61-63 superoxide dismutase 1 Homo sapiens 41-44 16679054-2 2006 The electrochemical activity of the SOD enzyme electrode was inhibited irreversibly by the addition of Al. Aluminum 103-105 superoxide dismutase 1 Homo sapiens 36-39 15050431-1 2004 Epidemiologic studies of endemic foci of amyotrophic lateral sclerosis (ALS) have shown low concentrations of Ca/Mg and high concentrations of Al/Mn in the drinking water and garden soil, which may play a causative role in the pathogenesis of endemic ALS. Aluminum 143-145 superoxide dismutase 1 Homo sapiens 72-75 15050431-1 2004 Epidemiologic studies of endemic foci of amyotrophic lateral sclerosis (ALS) have shown low concentrations of Ca/Mg and high concentrations of Al/Mn in the drinking water and garden soil, which may play a causative role in the pathogenesis of endemic ALS. Aluminum 143-145 superoxide dismutase 1 Homo sapiens 251-254 15050431-6 2004 We speculate that environmental factors such as chronic low-Ca/Mg high-Al condition play some causative role in the pathogenesis of Kii-ALS. Aluminum 71-73 superoxide dismutase 1 Homo sapiens 136-139 9788754-2 1998 A 400 mg dose of Al in the presence of citric acid inhibited cytosolic total and CN -sensitive superoxide dismutase activities of the cerebral hemisphere in 7- and 30-day treated chicks, whereas in 15-day treated chicks the enzyme activities were decreased in response to both doses in the presence of citric acid. Aluminum 17-19 superoxide dismutase 1 Homo sapiens 95-115 12561533-4 2002 Both serum aluminum and fluoride concentration are correlated inversely with GSH-Px activity, and correlated with MDA concentration and SOD activity. Aluminum 11-19 superoxide dismutase 1 Homo sapiens 136-139 11776410-5 2001 Superoxide dismutase (SOD)+catalase and vitamins C and E added in the culture medium as oxygen radical and free radical scavengers were efficient in preventing MDA production by aluminium, indicating that oxidative processes are one of the main pathways whereby this metal induces cytotoxicity. Aluminum 178-187 superoxide dismutase 1 Homo sapiens 0-20 11776410-5 2001 Superoxide dismutase (SOD)+catalase and vitamins C and E added in the culture medium as oxygen radical and free radical scavengers were efficient in preventing MDA production by aluminium, indicating that oxidative processes are one of the main pathways whereby this metal induces cytotoxicity. Aluminum 178-187 superoxide dismutase 1 Homo sapiens 22-25 9788754-8 1998 Activities of SOD and catalase of cerebral hemisphere and liver of 30-day old chicks were observed to be inhibited by in vitro incubation with different concentrations of Al. Aluminum 171-173 superoxide dismutase 1 Homo sapiens 14-17 9788754-9 1998 Our in vivo study demonstrates that only CN -sensitive SOD is susceptible to Al. Aluminum 77-79 superoxide dismutase 1 Homo sapiens 55-58 9788754-10 1998 Further, responses of SOD and catalase to Al is tissue specific. Aluminum 42-44 superoxide dismutase 1 Homo sapiens 22-25 9285887-0 1997 Aluminum effect on lipid peroxidation and on the activities of superoxide dismutase and catalase in the cerebral hemisphere and liver of young chicks. Aluminum 0-8 superoxide dismutase 1 Homo sapiens 63-83 9285887-3 1997 Aluminum (Al) treatment (100 mg dose) to chicks over 7 and 30 days resulted in a decrease in activities of cytosolic total and CN(-)-sensitive superoxide dismutase (SOD) in the cerebral hemisphere (CH). Aluminum 0-8 superoxide dismutase 1 Homo sapiens 143-163 9285887-3 1997 Aluminum (Al) treatment (100 mg dose) to chicks over 7 and 30 days resulted in a decrease in activities of cytosolic total and CN(-)-sensitive superoxide dismutase (SOD) in the cerebral hemisphere (CH). Aluminum 0-8 superoxide dismutase 1 Homo sapiens 165-168 9285887-3 1997 Aluminum (Al) treatment (100 mg dose) to chicks over 7 and 30 days resulted in a decrease in activities of cytosolic total and CN(-)-sensitive superoxide dismutase (SOD) in the cerebral hemisphere (CH). Aluminum 0-2 superoxide dismutase 1 Homo sapiens 143-163 9285887-3 1997 Aluminum (Al) treatment (100 mg dose) to chicks over 7 and 30 days resulted in a decrease in activities of cytosolic total and CN(-)-sensitive superoxide dismutase (SOD) in the cerebral hemisphere (CH). Aluminum 0-2 superoxide dismutase 1 Homo sapiens 165-168 9285887-4 1997 In the 15-day treated group, activities of cytosolic total, CN(-)-sensitive and CN(-)-insensitive SOD of CH were decreased in response to all doses of Al. Aluminum 151-153 superoxide dismutase 1 Homo sapiens 98-101 9285887-5 1997 In the liver, activities of cytosolic total and CN(-)-sensitive SOD were decreased in response to all doses of Al treatment for 7 and 15 days. Aluminum 111-113 superoxide dismutase 1 Homo sapiens 64-67 9285887-11 1997 These results suggest that decrease in activities in SOD and CAT in CH and liver of the chicks after Al treatment constitutes one of the factors for the mechanism of tissue injury by Al. Aluminum 101-103 superoxide dismutase 1 Homo sapiens 53-56 2370923-2 1990 SOD activity is impaired by several trace elements including aluminium and silicon which are found in increased levels in plasma and tissues of uremic man. Aluminum 61-70 superoxide dismutase 1 Homo sapiens 0-3 8036558-2 1994 The authors have evaluated the evolution of values of serum aluminium concentration (Als) in the whole pool of patients undergoing RDT in Piedmont in the years 1982-1990. Aluminum 60-69 superoxide dismutase 1 Homo sapiens 85-88 8036558-6 1994 The values of Als (distinguished by type of treatment of chronic renal failure) show end confirm the improvement of the situation of aluminium accumulation, specially as regards bicarbonate HD where the percentage of patients with Als > 100 micrograms/l decreases from 10.5% in 1986 to 1.7% in 1990. Aluminum 133-142 superoxide dismutase 1 Homo sapiens 14-17 2706418-1 1989 In a group of 19 rheumatoid arthritis (RA) patients with normal renal function, serum levels of aluminium (AlS) were monitored during treatment with drugs containing this metal (Al). Aluminum 96-105 superoxide dismutase 1 Homo sapiens 107-110 23199702-5 2013 Furthermore, the presence of aluminum induced lipid peroxidation and reduced the activity of erythrocyte antioxidant enzymes (SOD, CAT and GSHPx). Aluminum 29-37 superoxide dismutase 1 Homo sapiens 126-129 32585149-11 2020 In the ovaries, Al caused reduction in folliculogenesis and decreased SOD activity. Aluminum 16-18 superoxide dismutase 1 Homo sapiens 70-73 24211763-9 2013 SOD was increased after 6 h. Changes of investigated parameters were also seen after subacute Al treatment. Aluminum 94-96 superoxide dismutase 1 Homo sapiens 0-3 3685911-1 1987 Aluminium (AlS) and zinc (ZnS) concentrations in serum were measured in patients with rheumatoid arthritis (RA) with and without Al-containing drugs and compared with levels in healthy controls. Aluminum 0-9 superoxide dismutase 1 Homo sapiens 11-14 3685911-1 1987 Aluminium (AlS) and zinc (ZnS) concentrations in serum were measured in patients with rheumatoid arthritis (RA) with and without Al-containing drugs and compared with levels in healthy controls. Aluminum 0-2 superoxide dismutase 1 Homo sapiens 11-14 3685911-5 1987 The difference in AlS levels might be due not only to the intestinal absorption of Al from Al-containing drugs, but also to a slightly impaired renal function, serum creatinine being slightly but significantly higher (p less than 0.05) in the Al-treated RA group than in non-Al-treated one. Aluminum 83-85 superoxide dismutase 1 Homo sapiens 18-21 3685911-5 1987 The difference in AlS levels might be due not only to the intestinal absorption of Al from Al-containing drugs, but also to a slightly impaired renal function, serum creatinine being slightly but significantly higher (p less than 0.05) in the Al-treated RA group than in non-Al-treated one. Aluminum 83-85 superoxide dismutase 1 Homo sapiens 18-21 3685911-5 1987 The difference in AlS levels might be due not only to the intestinal absorption of Al from Al-containing drugs, but also to a slightly impaired renal function, serum creatinine being slightly but significantly higher (p less than 0.05) in the Al-treated RA group than in non-Al-treated one. Aluminum 83-85 superoxide dismutase 1 Homo sapiens 18-21 26076368-12 2015 The observed Al/glutathione and Hg/SOD-1 correlation could be adaptive responses against the chronic presence of mercury. Aluminum 13-15 superoxide dismutase 1 Homo sapiens 35-40 21687640-0 2011 Towards Al-induced manganese-containing superoxide dismutase inactivation and conformational changes: an integrating study with docking simulations. Aluminum 8-10 superoxide dismutase 1 Homo sapiens 40-60 20510457-4 2010 Our results suggest variable toxicity among the Al compounds tested: Al-S most potently affected neurons, with a full and irreversible inhibition of NMDAR and VDCC signaling at 500 microM. Aluminum 48-50 superoxide dismutase 1 Homo sapiens 69-73