PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25746764-0	2015	IL4 receptor alpha mediates enhanced glucose and glutamine metabolism to support breast cancer growth.	Glucose	37-44	interleukin 4	Mus musculus	0-3	
32127173-5	2020	Mechanistically, IL-4 treatment increased insulin-stimulated glucose uptake and Akt phosphorylation in skeletal muscle C2C12 cells, and inhibition of IL-4 signaling via ruxolitinib, a Janus kinase (JAK) inhibitor, attenuated IL-4-induced insulin sensitivity.	Glucose	61-68	interleukin 4	Mus musculus	17-21	
29098499-7	2018	The prolonged secretion of IL-4 was thought to substantially contribute to the improvement of glucose tolerance.	Glucose	94-101	interleukin 4	Mus musculus	27-31	
32640667-7	2020	In glucose-loaded macrophages, there was cellular induction of IL-4, IL-4 Ralpha, arginase-1, and CD163, indicating that high glucose skewed naive macrophages toward M2 phenotypes via an IL-4-IL-4Ralpha interaction.	Glucose	3-10	interleukin 4	Mus musculus	63-67	
32640667-7	2020	In glucose-loaded macrophages, there was cellular induction of IL-4, IL-4 Ralpha, arginase-1, and CD163, indicating that high glucose skewed naive macrophages toward M2 phenotypes via an IL-4-IL-4Ralpha interaction.	Glucose	3-10	interleukin 4	Mus musculus	69-73	
32640667-7	2020	In glucose-loaded macrophages, there was cellular induction of IL-4, IL-4 Ralpha, arginase-1, and CD163, indicating that high glucose skewed naive macrophages toward M2 phenotypes via an IL-4-IL-4Ralpha interaction.	Glucose	126-133	interleukin 4	Mus musculus	63-67	
32640667-7	2020	In glucose-loaded macrophages, there was cellular induction of IL-4, IL-4 Ralpha, arginase-1, and CD163, indicating that high glucose skewed naive macrophages toward M2 phenotypes via an IL-4-IL-4Ralpha interaction.	Glucose	126-133	interleukin 4	Mus musculus	69-73	
31814802-5	2019	IL-4 improved GLUT4 translocation and tended to elevate glucose uptake by boosting insulin signaling.	Glucose	56-63	interleukin 4	Mus musculus	0-4	
25746764-7	2015	In vitro, IL4-enhanced glucose consumption and lactate production in 4T1 cells was mediated by IL4Ralpha.	Glucose	23-30	interleukin 4	Mus musculus	10-13	
25746764-11	2015	Our results demonstrate that IL4R mediates enhanced glucose and glutamine metabolism in 4T1 cancer cells, and that IL4-induced growth is supported by IL4/IL4R-enhanced glutamine metabolism in both human and murine mammary cancer cells.	Glucose	52-59	interleukin 4	Mus musculus	29-32	
21894160-0	2012	Regulation of glucose/lipid metabolism and insulin sensitivity by interleukin-4.	Glucose	14-21	interleukin 4	Mus musculus	66-79	
21894160-3	2012	In this study, we focused on examining the putative regulation of glucose and lipid metabolism by IL-4.	Glucose	66-73	interleukin 4	Mus musculus	98-102	
21894160-7	2012	CONCLUSIONS: Our results suggest that IL-4 regulates glucose and lipid metabolism by promoting insulin sensitivity, glucose tolerance and inhibiting lipid deposits.	Glucose	53-60	interleukin 4	Mus musculus	38-42	
11489328-0	2001	Cell type specific and glucose responsive expression of interleukin-4 by using insulin promoter and water soluble lipopolymer.	Glucose	23-30	interleukin 4	Mus musculus	56-69	
11489328-3	2001	WSLP-pRIP-IL4 complex was characterized by pancreas beta-cell specific and glucose responsive expression of IL-4.	Glucose	75-82	interleukin 4	Mus musculus	108-112	
11489328-7	2001	The expression level of IL-4 by pRIP-IL4 increased with increasing concentration of glucose.	Glucose	84-91	interleukin 4	Mus musculus	24-28	
11592833-6	2001	We measured glucose levels weekly up to the age of 32 weeks, revealing that co-injection of PAGA-Il4 and PAGA-Il10 plasmids prevented the development of diabetes in 75% of the treated animals.	Glucose	12-19	interleukin 4	Mus musculus	97-100	
7479761-2	1995	To investigate the role of PI3-kinase and IRS-1 in insulin-stimulated glucose uptake we examined whether stimulation of insulin-sensitive cells with platelet-derived growth factor (PDGF) or with interleukin 4 (IL-4) stimulates glucose uptake; the activated PDGF receptor (PDGFR) directly binds and activates PI3-kinase, whereas the IL-4 receptor (IL-4R) activates PI3-kinase via IRS-1 or the IRS-1-related molecule 4PS.	Glucose	227-234	interleukin 4	Mus musculus	195-208	
7479761-2	1995	To investigate the role of PI3-kinase and IRS-1 in insulin-stimulated glucose uptake we examined whether stimulation of insulin-sensitive cells with platelet-derived growth factor (PDGF) or with interleukin 4 (IL-4) stimulates glucose uptake; the activated PDGF receptor (PDGFR) directly binds and activates PI3-kinase, whereas the IL-4 receptor (IL-4R) activates PI3-kinase via IRS-1 or the IRS-1-related molecule 4PS.	Glucose	227-234	interleukin 4	Mus musculus	210-214