PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15496408-6	2004	Treatment of MIN6 cells with okadaic acid, which inhibits the activity of protein phosphatases, abolishes the interaction of Pdx-1 with Hdac-1 and Hdac-2 on low levels of glucose, suggesting the requirement of a dephosphorylation event for this interaction to occur.	Glucose	171-178	histone deacetylase 2	Mus musculus	147-153	
15496408-7	2004	These data indicate that insulin gene expression is decreased on low levels of glucose by recruitment of Hdac-1 and Hdac-2 to the insulin promoter by the transcription factor Pdx-1.	Glucose	79-86	histone deacetylase 2	Mus musculus	116-122	
15496408-0	2004	The pancreatic duodenal homeobox-1 protein (Pdx-1) interacts with histone deacetylases Hdac-1 and Hdac-2 on low levels of glucose.	Glucose	122-129	histone deacetylase 2	Mus musculus	98-104	
15496408-3	2004	In this study, we demonstrate that the histone deacetylases Hdac-1 and Hdac-2 are rapidly recruited to the insulin promoter in the mouse insulinoma cell line MIN6 when cells are switched from high to low glucose media.	Glucose	204-211	histone deacetylase 2	Mus musculus	71-77	
29587244-9	2018	High concentrations of glucose increased HDAC1 and HDAC2 protein levels in cultured SMCs.	Glucose	23-30	histone deacetylase 2	Mus musculus	51-56	
28502041-3	2018	Our findings showed that the glucose administration increased phosphorylated Akt, phosphorylated CREB, exon 1- and exon 4-specific BDNF transcripts, and FGF1 transcripts that are associated with the epigenetic changes expected to open the chromatin and a reduction in histone deacetylase 2 (HDAC2) in neurons and astrocytes of the murine hippocampus.	Glucose	29-36	histone deacetylase 2	Mus musculus	268-289	
28502041-3	2018	Our findings showed that the glucose administration increased phosphorylated Akt, phosphorylated CREB, exon 1- and exon 4-specific BDNF transcripts, and FGF1 transcripts that are associated with the epigenetic changes expected to open the chromatin and a reduction in histone deacetylase 2 (HDAC2) in neurons and astrocytes of the murine hippocampus.	Glucose	29-36	histone deacetylase 2	Mus musculus	291-296