PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33860440-10 2021 While inhibiting mTOR by rapamycin or shmTOR significantly suppressed high glucose-induced activation of NF-kappaB and its regulators IKKbeta and IkappaBalpha, suggesting mTOR is the upstream regulator of NF-kappaB. Glucose 75-82 conserved helix-loop-helix ubiquitous kinase Mus musculus 134-141 25749152-5 2015 reduced blood glucose levels significantly and increased the protein expressions of insulin receptor beta, insulin receptor substrate 1, protein kinase B (Akt/PKB), IKKalpha, and IkappaBalpha. Glucose 14-21 conserved helix-loop-helix ubiquitous kinase Mus musculus 165-173 33864813-13 2021 The increased urine excretion of glucose and sodium was mediated by decreased renal SGLT2 expression due to inactivation of the IKKalpha/beta/NF-kappaB-induced inflammatory response. Glucose 33-40 conserved helix-loop-helix ubiquitous kinase Mus musculus 128-141