PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33192319-10	2020	Our data show increased claudin-5 and occludin expression in oxygen and glucose (OGD)-deprived murine brain capillary cerebellar endothelial cells (cerebEND) after STVNa treatment.	Glucose	72-79	occludin	Mus musculus	38-46	
33573189-4	2021	High glucose decreased occludin, claudin-5, zona occludens-1 (ZO-1) and zona occludens-2 (ZO-2) tight junctions production and altered the endothelial permeability.	Glucose	5-12	occludin	Mus musculus	23-31	
34266350-6	2021	In the in vitro experiments, elevated endothelial permeability and decreased expression of occludin and KLF2 were observed in high glucose-challenged endothelial cells, which were significantly alleviated by Azilsartan.	Glucose	131-138	occludin	Mus musculus	91-99	
34266350-7	2021	Lastly, the silencing of KLF2 abolished the protective effects of Azilsartan against the high glucose-induced expression of occludin and endothelial monolayer permeability in bEnd.3 brain endothelial cells.	Glucose	94-101	occludin	Mus musculus	124-132	
28114578-10	2017	Results: High glucose significantly reduced ZO-1 and occludin protein levels, which was associated with reduced cell adhesion.	Glucose	14-21	occludin	Mus musculus	53-61	
28776759-6	2017	We further demonstrate that the low-glucose-induced disruption of occludin and Caludin5 as well as activation of autophagy was abrogated by melatonin-mediated blockade of nitrosative stress in vitro.	Glucose	36-43	occludin	Mus musculus	66-74	
31603990-8	2020	Meanwhile, our study also showed that the over-expression of cystatin C greatly enhanced caveolin-1 expression, which later increased occludin expression in oxygen-glucose deprivation-exposed brain microvascular endothelial cells.	Glucose	164-171	occludin	Mus musculus	134-142	
29136627-7	2017	High-glucose culture conditions significantly reduced occludin and ZO-1 levels in REC, and TLR4 siRNA treatment restored levels to baseline.	Glucose	5-12	occludin	Mus musculus	54-62	
24244596-7	2013	RESULTS: High glucose suppresses occludin expression and disrupts occludin/ZO-1 translocation in GEnCs.	Glucose	14-21	occludin	Mus musculus	33-41	
24244596-7	2013	RESULTS: High glucose suppresses occludin expression and disrupts occludin/ZO-1 translocation in GEnCs.	Glucose	14-21	occludin	Mus musculus	66-74	
24244596-10	2013	Simvastatin prevented high glucose or hyperglycemia-induced dysregulation of occludin and ZO-1 by inhibition of RhoA/ROCK1 signaling in cultured GEnCs and in db/db mice with early-stage DN.	Glucose	27-34	occludin	Mus musculus	77-85	
24244596-11	2013	CONCLUSION: Our results indicate that activation of RhoA/ROCK1 by high glucose disrupts the expression and translocation of occludin/ZO-1 and that simvastatin alleviates occludin/ZO-1 dysregulation and albuminuria by suppressing RhoA/ROCK1 signaling during early-stage DN.	Glucose	71-78	occludin	Mus musculus	124-132