PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11287749-2	2001	However, when cells are in suspension or in the presence of cytochalasin D which disrupts the intracellular network of actin microfilaments, TPA loses its ability to stimulate tyrosine phosphorylation of FAK and paxillin but it still activates mitogen-activated protein kinase (MAPK) and induces PKC translocation from cytosol to the membrane in HepG2 cells.	Cytochalasin D	60-74	paxillin	Homo sapiens	212-220	
12827288-4	2003	We also show that CD-induced actin aggregates bind the F-actin-selective drug phalloidin and associate with proteins involved in cell signaling as well as with receptors and endosomal markers (active MAP kinases, paxillin, erbB2, transferrin, Rab-5), but not with clathrin, protein kinase A, protein tyrosine phosphatase 1B, or tubulin.	Cytochalasin D	18-20	paxillin	Homo sapiens	213-221	
10455189-12	1999	Pretreatment with cytochalasin D, which disrupts actin microfilaments, prevented the calcitonin-induced HEF1 and paxillin phosphorylation.	Cytochalasin D	18-32	paxillin	Homo sapiens	113-121	
11121866-7	2001	Cytochalasin D (0.3 microM), which inhibits actin polymerization, reduced the ability of BB to stimulate tyrosine phosphorylation of p125(FAK) and paxillin.	Cytochalasin D	0-14	paxillin	Homo sapiens	147-155	
10804218-9	2000	Cytochalasin D, an actin depolymerizing agent, decreases tyrosine phosphorylation of FAK and paxillin and their association with beta1 integrin and causes a dose-dependent increase in the abundance of insoluble FAK and paxillin complexes.	Cytochalasin D	0-14	paxillin	Homo sapiens	93-101	
10804218-9	2000	Cytochalasin D, an actin depolymerizing agent, decreases tyrosine phosphorylation of FAK and paxillin and their association with beta1 integrin and causes a dose-dependent increase in the abundance of insoluble FAK and paxillin complexes.	Cytochalasin D	0-14	paxillin	Homo sapiens	219-227	
10208419-6	1999	Tyrosine phosphorylation of FAK, paxillin and p130Cas was inhibited by cytochalasin D or two specific inhibitors of phosphatidylinositol-3" kinase (PI-3" kinase), wortmannin and LY294002, indicating that their tyrosine phosphorylation depends on the formation of actin stress fiber and activation of PI-3" kinase.	Cytochalasin D	71-85	paxillin	Homo sapiens	33-41	
9489713-3	1998	In contrast, the increased tyrosine phosphorylations of FAK and paxillin were inhibited by inclusion of either cytochalasin D or mevastatin, agents that disrupt the cytoskeleton.	Cytochalasin D	111-125	paxillin	Homo sapiens	64-72	
8626373-8	1996	In contrast, cytochalasin D eliminated neurite outgrowth, cell spreading, and the tyrosine phosphorylation of paxillin and focal adhesion kinase.	Cytochalasin D	13-27	paxillin	Homo sapiens	110-118