PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16672691-6	2006	Inhibition of phosphoinositide 3-kinase (PI3K), but not JNK, significantly decreased the amount of active MMP-2 following cytochalasin D stimulation with a concurrent decrease in MT1-MMP protein.	Cytochalasin D	122-136	matrix metallopeptidase 2	Homo sapiens	106-111	
17460268-3	2007	RESULTS: Treatment of HTM cells with cytochalasin D and latrunculin A led to significant activation of MMP-2, p38 MAPK, and ERK1/2, which appeared to correlate with changes in cell morphology and actin depolymerization.	Cytochalasin D	37-51	matrix metallopeptidase 2	Homo sapiens	103-108	
11691580-4	2001	Disruption of the actin stress fibers by CD induced a moderate increase of MMP-2 mRNA and a much larger stimulation of MMP-3, -9, -13 and -14 mRNAs.	Cytochalasin D	41-43	matrix metallopeptidase 2	Homo sapiens	75-80	
11691580-8	2001	The CD-induced up-regulation of gene expression was largely repressed by blocking protein synthesis by cycloheximide for all the MMPs, by inhibiting the tyrosine-kinases of the src family by herbimycin A for all MMPs, except MMP-2, and by inhibiting the TPA-inducible PKC isoforms by bisindoyl maleimide for all MMPs, except MMP-14.	Cytochalasin D	4-6	matrix metallopeptidase 2	Homo sapiens	225-230	
11727833-7	2001	Activation of MMP-2 in HRSF could be induced by treatment with concanavalin A (ConA) or cytochalasin D, as was shown for other cell types.	Cytochalasin D	88-102	matrix metallopeptidase 2	Homo sapiens	14-19