PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12588696-7	2002	Serum concentrations of beta-carotene and zeaxanthin + lutein were significantly associated with the risk of breast cancer in p53-positive and p53-negative cancers.	beta Carotene	24-37	tumor protein p53	Homo sapiens	126-129	
12588696-7	2002	Serum concentrations of beta-carotene and zeaxanthin + lutein were significantly associated with the risk of breast cancer in p53-positive and p53-negative cancers.	beta Carotene	24-37	tumor protein p53	Homo sapiens	143-146	
19723050-5	2009	We found that beta-carotene (100 micromol/L) induced apoptosis (determined by cell viability), DNA fragmentation, and the protein levels of p53 and Bcl-2 in AGS cells.	beta Carotene	14-27	tumor protein p53	Homo sapiens	140-143	
19452524-8	2009	This was especially true for TP53 transversion mutations and dietary antioxidants (OR for beta-carotene 0.51 95% CI 0.27, 0.97, p trend 0.03; alpha-tocopherol 0.41 95% CI 0.20, 0.84, p trend 0.02) Beta-carotene and ibuprofen significantly altered risk of KRAS2 tumors.	beta Carotene	90-103	tumor protein p53	Homo sapiens	29-33	
19452524-8	2009	This was especially true for TP53 transversion mutations and dietary antioxidants (OR for beta-carotene 0.51 95% CI 0.27, 0.97, p trend 0.03; alpha-tocopherol 0.41 95% CI 0.20, 0.84, p trend 0.02) Beta-carotene and ibuprofen significantly altered risk of KRAS2 tumors.	beta Carotene	197-210	tumor protein p53	Homo sapiens	29-33	
19723050-7	2009	beta-Carotene-induced alterations, including an increase in DNA fragmentation and p53 levels and a decrease in nuclear ATM and cellular Bcl-2 levels, were inhibited in the cells transfected with full-length ATM cDNA compared to wild-type cells or the cells transfected with control vector plasmid control DNA vector (pcDNA).	beta Carotene	0-13	tumor protein p53	Homo sapiens	82-85	
19723050-8	2009	In conclusion, beta-carotene induces apoptosis by increasing apoptotic protein p53 and decreasing anti-apoptotic Bcl-2 as well as nuclear ATM in AGS cells.	beta Carotene	15-28	tumor protein p53	Homo sapiens	79-82	
15073048-0	2004	beta-Carotene exacerbates DNA oxidative damage and modifies p53-related pathways of cell proliferation and apoptosis in cultured cells exposed to tobacco smoke condensate.	beta Carotene	0-13	tumor protein p53	Homo sapiens	60-63	
15073048-8	2004	In contrast, fibroblasts treated with tar and beta-carotene, after an initial arrest of cell growth at 12 h, re-entered in cell cycle and were unable to undergo apoptosis at 36 h. Concomitantly, their p53 expression, after an increase at 12 h, progressively returned at basal levels at 36 h by a mechanism independent of Mdm2.	beta Carotene	46-59	tumor protein p53	Homo sapiens	201-204	
19142877-5	2009	RESULTS: The positivity for total p53, RARbeta, cyclin D1, and PCNA was nonsignificantly lower among lung cancer patients who were assigned to receive beta-carotene than those who were assigned to receive beta-carotene placebo.	beta Carotene	151-164	tumor protein p53	Homo sapiens	34-37	
20067883-15	2009	beta-carotene, lycopene and all-trans retinoic acid alone and in combination with docetaxel were found to influence the expression of bcl-2 and p53 antigen in the cells examined.	beta Carotene	0-13	tumor protein p53	Homo sapiens	144-147